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phenylacetic acid/דלקת
הקישור נשמר בלוח
עמוד 1 מ 69 תוצאות
Phenylacetic acids and the structurally related non-steroidal anti-inflammatory drug diclofenac bind to specific gamma-hydroxybutyric acid sites in rat brain.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Gamma-Hydroxybutyric acid (GHB) is a proposed neurotransmitter or neuromodulator with a yet unresolved mechanism of action. GHB binds to both specific high-affinity GHB binding sites and to gamma-aminobutyric acid subtype B (GABA(B)) receptors in the brain. To separate specific GHB effects from
Discovery of 2-oxy-2-phenylacetic acid substituted naphthalene sulfonamide derivatives as potent KEAP1-NRF2 protein-protein interaction inhibitors for inflammatory conditions
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Nuclear factor erythroid 2-related factor 2 (NRF2) is a pleiotropic transcription factor which regulates the constitutive and inducible transcription of a wide array of genes and confers protection against a variety of pathologies. Directly disrupting Kelch-like ECH-associated protein 1 (KEAP1)-NRF2
Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
A novel class of phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore attached to its C-2, C-3 or C-4 position was designed for evaluation as anti-inflammatory (AI) agents. A number of compounds exhibited a combination of potent in vitro cyclooxygenase-2
The uraemic toxin phenylacetic acid contributes to inflammation by priming polymorphonuclear leucocytes.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND
The activation of polymorphonuclear leucocytes (PMNLs) causes inflammation and as a result cardiovascular disease, which is a main risk factor for increased morbidity and mortality in patients with chronic kidney disease. Toxins accumulating in uraemic patients play a major role in
Anti-inflammatory and related properties of 2-(2,4-dichlorophenoxy)phenylacetic acid (fenclofenac).
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Fenclofenac was shown to possess anti-inflammatory, antinociceptive and antipyretic properties as measured by tests in rats that detect clinically active compounds. In a chronic test for assessing anti-inflammatory activity (established adjuvant arthritis), it was approximately equipotent to
[Synthesis and anti-inflammatory activity of (2-pyrimidinylamino)phenylacetic acid derivatives].
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Proceedings: Anti-inflammatory, analgesic and other related actions of DKA-9, 3-methoxy-5-(p-chlorophenyl)-phenylacetic acid.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
2-(2,4-dichlorophenoxy) phenylacetic acid (fenclofenac): one of a novel series of anti-inflammatory compounds with low ulcerogenic potential.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Covalent binding of phenylacetic acid to protein in incubations with freshly isolated rat hepatocytes.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Phenylacetic acid (PAA) represents a substructure of a class of nonsteroidal anti-inflammatory carboxylic acid-containing drugs capable of undergoing metabolic activation in the liver to acylcoenzyme A (CoA)- and/or acyl glucuronide-linked metabolites that are proposed to be associated with the
Anti-inflammatory, analgesic and other related actions of 4'-chloro-5-methoxy-3-biphenylylacetic acid (DKA-9).
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
4'-Chloro-5-methoxy-3-biphenylylacetic acid (DKA-9) is a novel phenylacetic acid derivative with marked anti-inflammatory, analgesic and antipyretic activities. DKA-9 was approximately 2 times and 25 times more effective than ibuprofen in inhibiting carrageenin-induced paw edema and adjuvant-induced
4-(1,2-Benzisothiazol-3-yl)alkanoic and phenylalkanoic acids: synthesis and anti-inflammatory, analgesic and antipyretic activities.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Continuing their studies on benzisothiazolyl derivatives, Authors refer to the preparation and pharmacological properties of 4-(1,2-benzisothiazol-3-yl) alkanoic and phenylalkanoic acids. All substances were tested for anti-inflammatory, analgesic and antipyretic properties. As reference compounds,
Pharmacology of the potent new non-steroidal anti-inflammatory agent aceclofenac.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Aceclofenac (2-[(2,6-dichlorophenyl) amine]phenylacetoxyacetic acid; CAS 89796-99-6) is a new orally effective non-steroidal anti-inflammatory agent of the phenylacetic acid group which showed remarkable anti-inflammatory, analgesic, and antipyretic properties. Hence, aceclofenac possesses a potent
Acute poisoning due to non-steroidal anti-inflammatory drugs. Clinical features and management.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Despite the widespread use of non-steroidal anti-inflammatory drugs (NSAIDs), the current number of reported cases of poisoning is small. However, with the introduction of 'over-the-counter' preparations of NSAIDs in some countries (e.g. ibuprofen in the UK and USA) an increased incidence of acute
Photochemical studies on the anti-inflammatory drug diclofenac.
רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Irradiation with UVA light of the anti-inflammatory drug diclofenac [2-(2,6-dichloroanilino)phenylacetic acid] in aqueous buffer or methanol solution leads to sequential loss of both chlorine substituents and ring closure to carbazole-1-acetic acid as the major product. Minor products result from
המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע
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הקלד סימפטום או מחלה וקרא על צמחי מרפא שעשויים לעזור, הקלד עשב וראה מחלות ותסמינים שהוא משמש נגד.
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