This arm received placebo in the first period and laxative tea in the second period (after washout period of 9 days).

This arm received laxative tea in the first intervention period and placebo in the second intervention period (after washout period of 9 days).

Placebo in the first period and laxative tea in the second period (after washout period)

Placebo First Crossover

Laxative tea in the first period and placebo in the second period (after washout period).

Laxative Tea First Crossover

Total

Sex: Female, Male

Region of Enrollment

The number of patients who had not evacuated on day 5 of each intervention period was obtained using questions 1 and 9 of the Scale for Assessment of Constipation Symptoms based on: 1) How many times have you had a bowel movement in the last 24 hours?; 9) Classification of bowel habit on a scale of 1 (terrible) to 5 (excellent).

Placebo administered three times a day in either first intervention period or second intervention period.

Placebo

Laxative tea administered three times a day in either first intervention period or second intervention period.

Laxative Tea

Number of Patients With no Evacuation After Each Intervention Period

Radiologic technique consisting of the ingestion of radiopaque markers, followed by a simple x-ray of the abdomen on day 3 of each intervention period. Standard formula, regarding markers ingested, time of ingestion and markers still present on the colon (counted by radiologist unaware of the treatment allocation), provided transit time.

Intestinal Transit Time

First Intervention

Washout Period

Second Intervention

Dr. Paulo Dornelles Picon

Chronic Constipation

In order to produce similar taste and color, 7 drops of caramel color and 10 drops of orange essence were mixed into 1.6 liters of boiling water. The patients received 150 ml of placebo 3 times a day for 5 days.

The laxative tea was prepared using 1 gram of grinded plant into 150 ml of water, left under infusion by 5 minutes. Patients received 150 ml of tea 3 times a day for 5 days.

pimpinella monoica/חומר משלשל

Laxative Effectiveness of a Phytotherapeutic Tea

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע