piperidine/כאב ראש

הקישור נשמר בלוח

בחר סוג מיון

9 תוצאות

Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Calcitonin gene-related peptide (CGRP) is a potent neuropeptide that plays a key role in the pathophysiology of migraine headache. CGRP levels in the cranial circulation are increased during a migraine attack, and CGRP itself has been shown to trigger migraine-like headache. The correlation between

Leishmanicidal activity of the crude extract, fractions and major piperidine alkaloids from the flowers of Senna spectabilis.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Senna spectabilis (sin. Cassia excelsa, C. spectabilis) is an endemic tree of South America and Africa, very common in Brazil, where it is known as "canafistula-de-besouro" and "cassia-do-nordeste". In folk medicine, this plant is indicated for the treatment of constipation, insomnia, anxiety,

Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The sensory neuropeptide calcitonin gene-related peptide (CGRP) plays a role in primary headaches, and CGRP receptor antagonists are effective in migraine treatment. CGRP is a potent vasodilator, raising the possibility that antagonism of its receptor could have cardiovascular effects. We therefore

Methylphenidate HCl: therapy for attention deficit hyperactivity disorder.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Methylphenidate is a first-line therapy for attention deficit hyperactivity disorder, the most prevalent neuropsychiatric disorder of childhood. The compound is a piperidine and the D-threo-isomer is considered the biologically active form. The compound is available in multiple short- and

Characterisation of the effects of a non-peptide CGRP receptor antagonist in SK-N-MC cells and isolated human cerebral arteries.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The cerebral circulation is innervated by calcitonin gene-related peptide (CGRP) containing fibers originating in the trigeminal ganglion. During a migraine attack, there is a release of CGRP in conjunction with the head pain, and triptan administration abolishes both the CGRP release and the pain

Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Ampakines act as positive allosteric modulators of AMPA-type glutamate receptors and facilitate hippocampal long-term potentiation (LTP), a mechanism associated with memory storage and consolidation. The present study investigated the acute effects of farampator, 1-(benzofurazan-5-ylcarbonyl)

Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

BACKGROUND Lasmiditan (also known as COL-144 and LY573144; 2,4,6-trifluoro-N-[6-[(1-methylpiperidin-4-yl)carbonyl]pyridin-2yl]benzamide) is a high-affinity, highly selective serotonin (5-HT) 5-HT(1F) receptor agonist. RESULTS In vitro binding studies show a K(i) value of 2.21 nM at the 5-HT(1F)

Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine ^®) and Potential Applications

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Black pepper (Piper nigrum L.) has been employed in medicine (epilepsy, headaches, and diabetes), where its effects are mainly attributed to a nitrogen alkaloid called piperidine (1-(1-[1,3-benzodioxol-5-yl]-1-oxo-2,4 pentenyl) piperidine). Piperine co-administered with vitamins and minerals

The pharmacology of donepezil: a new treatment of Alzheimer's disease.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Donepezil (donepezil hydrochloride, E-2020, Aricept, Eisai), launched in March 1997, was the first drug to be marketed for the symptomatic treatment of Alzheimer's disease (AD) in the UK. It had been launched a year earlier in the US where clinicians had already had experience of tacrine (THA).

הצטרפו לדף הפייסבוק שלנו

Herbal & Natural Medicine

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע

עובד ב 55 שפות
מרפא צמחי מרפא מגובה על ידי מדע
זיהוי עשבי תיבול על ידי דימוי
מפת GPS אינטראקטיבית - תייגו עשבי תיבול במיקום (בקרוב)
קרא פרסומים מדעיים הקשורים לחיפוש שלך
חפש עשבי מרפא על פי השפעותיהם
ארגן את תחומי העניין שלך והתעדכן במחקר החדשות, הניסויים הקליניים והפטנטים

הקלד סימפטום או מחלה וקרא על צמחי מרפא שעשויים לעזור, הקלד עשב וראה מחלות ותסמינים שהוא משמש נגד.
* כל המידע מבוסס על מחקר מדעי שפורסם

piperidine/כאב ראש

Leishmanicidal activity of the crude extract, fractions and major piperidine alkaloids from the flowers of Senna spectabilis.

Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries.

Methylphenidate HCl: therapy for attention deficit hyperactivity disorder.

Characterisation of the effects of a non-peptide CGRP receptor antagonist in SK-N-MC cells and isolated human cerebral arteries.

Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers.

Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan.

Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine ®) and Potential Applications

The pharmacology of donepezil: a new treatment of Alzheimer's disease.

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע

Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine ^®) and Potential Applications