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potassium chloride/פרכוס אפילפטי

הקישור נשמר בלוח
עמוד 1 מ 64 תוצאות
Cardiac arrest and resuscitation were used to induce brain damage and susceptibility to sound-triggered seizures in Sprague-Dawley rats. Glucose preloading was used to vary seizure susceptibility. Because loop diuretics can block these seizures, we investigated changes in KCC2, a potassium-chloride

Agents which block potassium-chloride cotransport prevent sound-triggered seizures in post-ischemic audiogenic seizure-prone rats.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The purpose of this study was to determine whether the loop diuretics furosemide, bumetanide and ethacrynic acid, which block the KCC1 potassium-chloride transporter in the kidney loop of Henle and the KCC2 potassium-chloride transporter in neuronal membranes, would prevent sound-triggered seizures

Apparent seizure and atrial fibrillation associated with paliperidone.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
OBJECTIVE A case of apparent seizure and atrial fibrillation associated with paliperidone is reported. CONCLUSIONS A 46-year-old man arrived at the emergency room (ER) via ambulance. Earlier that morning, his wife observed him awakening in a panic, drifting back to sleep, and then subsequently

Possible mechanism of digoxin-induced convulsions.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Intraventricular (IVT) administration of digoxin (7.5 micrograms) induced 'popcorn-type' convulsions in rats. Though the convulsions looked similar to morphine-induced seizures, naloxone failed to antagonize these effects. Other anticonvulsants like phenobarbitone, ethosuximide, or GABAergic

Coordinated downregulation of KCC2 and GABA A receptor contributes to inhibitory dysfunction during seizure induction

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The GABAA receptor (GABAAR) is the main inhibitory receptor in the adult mammalian brain. GABAAR function is dependent on its expression, distribution, and the chloride (Cl-) transmembrane gradient, which is determined by the potassium-chloride

Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Seizure susceptibility to neurological insults, including chemical convulsants, is age-dependent and most likely reflective of overall differences in brain excitability. The molecular and cellular mechanisms underlying development-dependent seizure susceptibility remain to be fully understood.

Effect of keto-acidosis on seizure occurrence in diabetic patients.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
It has been observed anecdotally that diabetics are usually non-ketotic at the time of their seizure presentation. In order to establish some validity on this observation, we reviewed the medical records of patients with diagnoses of diabetes and seizure. Study subjects were diabetics presenting

Altered expression of GABAA receptors (α4, γ2 subunit), potassium chloride cotransporter 2 and astrogliosis in tremor rat hippocampus.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Impaired GABAergic inhibitory neurotransmission plays an essential role in the pathogenesis of epilepsy. GABA(A) receptor (GABA(A)R), potassium chloride cotransporter 2 (KCC2) and astrocytes are of particular importance to GABAergic transmission and thus involved in the development of increased

Potassium chloride-induced fetal demise: a retrospective cohort study of efficacy and safety.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
OBJECTIVE Induction of fetal demise before second-trimester termination is performed for a number of reasons. One method for inducing fetal demise is via sonographically guided intracardiac potassium chloride (KCl) injection. We performed a retrospective cohort study to determine the efficacy and

Mutation analysis of the potassium chloride cotransporter KCC3 (SLC12A6) in rolandic and idiopathic generalized epilepsy.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Genetic predisposition plays a major role in the etiology of idiopathic epilepsies. The common epilepsy syndromes display a complex pattern of inheritance, with an unknown number of genes contributing to seizure susceptibility. During the last decade linkage studies have narrowed down several

Microarray Noninvasive Neuronal Seizure Recordings from Intact Larval Zebrafish.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Zebrafish epilepsy models are emerging tools in experimental epilepsy. Zebrafish larvae, in particular, are advantageous because they can be easily genetically altered and used for developmental and drug studies since agents applied to the bath penetrate the organism easily. Methods for

Regulation of seizure-induced MeCP2 Ser421 phosphorylation in the developing brain.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Neonatal seizures disrupt normal synaptic maturation and often lead to later-life epilepsy and cognitive deficits. During early life, the brain exhibits heightened synaptic plasticity, in part due to a developmental overabundance of CaV1.2 L-type voltage gated calcium (Ca2+) channels (LT-VGCCs) and

The effect of serum potassium on theophylline-induced seizures.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Generalized seizures may be associated with therapeutic or intentional theophylline overdose. Toxic levels of theophylline are also associated with a fall in potassium which could potentiate theophylline-induced seizures. To evaluate the role of serum potassium concentration in theophylline-induced

Reducing premature KCC2 expression rescues seizure susceptibility and spine morphology in atypical febrile seizures.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Atypical febrile seizures are considered a risk factor for epilepsy onset and cognitive impairments later in life. Patients with temporal lobe epilepsy and a history of atypical febrile seizures often carry a cortical malformation. This association has led to the hypothesis that the presence of a

Effect of a novel prolonged febrile seizure model on GABA associated ion channels.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Prolonged febrile seizures are usually modelled in animals using hyperthermia as an inducer. In this study, a modified simple febrile seizure model using a combination of lipopolysaccharide (LPS) and kainic acid (KA) was used to develop a prolonged febrile seizure animal model, which we used to
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