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progesterone/סרטן השד

הקישור נשמר בלוח
עמוד 1 מ 42 תוצאות

Targeted treatment for patients with estrogen receptor negative and progesterone receptor negative breast cancers

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION Treatments for estrogen receptor and progesterone receptor negative breast cancer or estrogen receptor, progesterone receptor and c-erbB2 negative (triple negative) breast cancer are provided. BACKGROUND OF THE INVENTION Cancer/testis (CT) antigens constitute a unique group of

Progesterone antagonists such as CDB-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer, etc

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION The present invention relates to compositions and methods for treating an estrogen-dependent condition. More specifically, the present invention relates to compositions comprising one or more progesterone antagonists for suppressing endometrial proliferation. BACKGROUND OF THE

Progesterone antagonists such as CDB-4124 in the treatment of endometriosis, uterine fibroids, dysmenorrhea, breast cancer, etc

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION The present invention relates to compositions and methods for treating an estrogen-dependent condition. More specifically, the present invention relates to compositions comprising one or more progesterone antagonists for suppressing endometrial proliferation. BACKGROUND OF THE

Method of progesterone delivery and affect thereof

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND OF THE INVENTION Progesterone is a naturally occurring steroid which is the main steroid secreted by women during their reproductive years. This steroid has been studied extensively and has been found to be a major precursor in the biosynthesis of most other steroids, particularly

Progesterone receptor-regulated gene expression and methods related thereto

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION This invention generally relates to expression profiles of genes that are regulated by progesterone receptors, and particularly by progesterone receptor isoforms PR-A and PR-B, and to the use of such genes in methods for identifying progesterone receptor agonist and antagonist

Progesterone receptor antagonists

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-dien-11-aryl derivatives of formula I with progesterone-antagonizing action and methods of production thereof, use thereof for the treatment and/or prevention of diseases and use thereof for the production of medicinal products

High affinity monoclonal antibody for recognizing the progesterone receptor (PR) and method for creating the antibody

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION The present invention relates to the field of antibodies. In particular the present invention discloses an antibody ideal for immunohistochemical staining without difficult target retrieval procedures. BACKGROUND OF THE INVENTION A standard technique for medical diagnosis is

Method for treatment of primary hormone resistant endometrial and breast cancers

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION The invention provides a method for treatment of primary progesterone receptor-negative (PR-) endometrial cancer comprising administering (i) cridanimod or a salt or an ester thereof and (ii) a progesterone receptor (PR) agonist. The invention further provides a method for

Means and methods for molecular classification of breast cancer

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
INCORPORATION OF SEQUENCE LISTING Incorporated herein in its entirety and submitted herewith is the computer readable Sequence Listing. The Sequence Listing is disclosed on a computer-readable ASCII text file titled "SequenceListing294-411CON.txt", date modified on Oct. 28, 2015. The sequence.txt

Means and methods for molecular classification of breast cancer

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
INCORPORATION OF SEQUENCE LISTING Incorporated herein in its entirety and submitted herewith is the computer readable Sequence Listing for the above-identified Application. The Sequence Listing is disclosed on a computer-readable ASCII text file titled "SequenceListing294-411.txt", date modified on

Composite metastasis score with weighted coefficients for predicting breast cancer metastasis, and uses thereof

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION The present invention relates to prognosis of breast cancer metastasis. In particular, the present invention relates to a multi-gene prognostic signature typically comprising 14 genes (which may be referred to herein as a "metastasis score" ("MS")) in combination with
BACKGROUND OF THE INVENTION Estrogen receptor .alpha. (ER.alpha.) is a member of the steroid/nuclear receptor family of transcription regulators and mediates cell growth and metastases, and resistance to apoptosis and immunosurveillance (see references 1-5). ER.alpha. is activated by binding of

Association of the DNA methylation profile of the CYP1B1 gene with response to adjuvant therapy in breast cancer

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION Particular aspects relate generally to DNA methylation and hormone receptor biology, and particularly to prognostic and diagnostic methods relating to cancer (e.g., breast cancer), and to methylation marker-based methods for predicting response to endocrine (e.g.,

System for thermometry-based breast cancer risk-assessment

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
FIELD OF THE INVENTION The present invention is in the field of biotechnology and specifically relates to the field of breast cancer screening in women. BACKGROUND TO THE PRESENT INVENTION--THE RELATED ART For well over twenty years, thermometric assessment of the human female breast surface has

Prognostic biomarkers to predict overall survival and metastatic disease in patients with triple negative breast cancer

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND (a) Field The present invention relates to a method for prognosing or predicting overall survival (OS) or metastasis in a subject with triple negative (TN) breast cancer. More specifically, the invention relates to two sets of biomarkers, one set useful for prognosing or predicting OS in
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