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proline/פרכוס אפילפטי

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
עמוד 1 מ 113 תוצאות

Identification of a Premature Termination Mutation in the Proline-Rich Transmembrane Protein 2 Gene in a Chinese Family with Febrile Seizures.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Febrile seizures (FS), the most frequent type of seizures in children, occur in neurologically normal infants and children between the ages of 3 months and 5 years with genetic predisposition. The aim of this study was to identify the responsible gene in a four-generation Chinese Han pedigree with
A 21-year-old woman presented with a chief complaint of generalized tonic-clonic seizures occurring once a month at night since the age of 14. The patient was treated with clonazepam plus levetiracetam, but seizure frequency was not reduced. After the detailed re-examination of her history of

Retrograde amnesia in neonatal chicks: induction by L-proline is not accompanied by occult seizures.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם

Retroactive amnesia induced in chicks by the proline analog L-baikiain, without EEG seizures or depression.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם

NMDA receptor-mediated depolarizing action of proline on CA1 pyramidal cells.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
This study investigated the actions of proline on CA1 hippocampal pyramidal cells with use of slice preparations. Bath-applied L-proline first induced these cells to fire multiple orthodromic population spikes in response to a single stimulus and then blocked their response to both orthodromic and

Proline-induced potentiation of glutamate transmission.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The amino acid proline has long been suspected to serve as a modulator of synaptic transmission in the mammalian brain, but no such function has been identified. The selective expression of high affinity proline transport by a subset of glutamate pathways suggested that proline might play a role in

Proline and proline derivatives as anticonvulsants.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
1. The anticonvulsant properties of L-proline, of proline derivatives (trans-4-hydroxy-L-proline, cis-4-hydroxy-D-proline, 3,4-dehydro-D,L-proline) and of D- and L-pipecolic acid were studied alone and in combination with vigabatrin (R/S-4-aminohex-5-enoic acid). 3-Mercaptopropionic acid and

Behavioral changes induced by long-term proline exposure are reversed by antipsychotics in zebrafish.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Hyperprolinemia is an inherited disorder of proline metabolism and patients affected by this disease may present neurological manifestations, including seizures and cognitive dysfunctions. Moreover, an association between adulthood schizoaffective disorders and moderate hyperprolinemia has been

Single nucleotide variations in CLCN6 identified in patients with benign partial epilepsies in infancy and/or febrile seizures.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Nucleotide alterations in the gene encoding proline-rich transmembrane protein 2 (PRRT2) have been identified in most patients with benign partial epilepsies in infancy (BPEI)/benign familial infantile epilepsy (BFIE). However, not all patients harbor these PRRT2 mutations, indicating the
We describe two Thai families with Norrie disease (ND) in three generations, including 10 affected males and one manifesting female. All affected males in each family had severely defective eye development with complete loss of vision. In addition, three male patients (one from family 1 and two from

Seizures and selective CA-1 hippocampal lesions induced by an excitotoxic cyanide metabolite, 2-iminothiazolidine-4-carboxylic acid.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Excitatory amino acid (EAA)-like and excitotoxic properties of the secondary metabolite of cyanide, 2-iminothiazolidine-4-carboxylic acid, (2-ICA) were evaluated because of its possible role in cyanide-induced neurotoxicity. Intracerebroventricular (i.c.v.) injections of 2-ICA in mice produced

2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
We previously demonstrated that 2-iminothiazolidine-4-carboxylic acid (2-ICA), formed by cyanide reacting with cysteine, caused glutamate antagonist-sensitive seizures when injected i.c.v. (intracerebroventricular) in mice and produced hippocampal CA1 damage following i.c.v. infusion in rats. In

Long-term proline exposure alters nucleotide catabolism and ectonucleotidase gene expression in zebrafish brain.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Hyperprolinemia is an inherited disorder of proline metabolism and hyperprolinemic patients can present neurological manifestations, such as seizures cognitive dysfunctions, and psychotic disorders. However, the underlying mechanisms of these symptoms are still unclear. Since adenine nucleotides

Blockade of hyperbaric oxygen induced seizures by excitatory amino acid antagonists.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The effectiveness of several excitatory amino acid antagonists to delay or block seizures induced by oxygen at high pressure was examined in mice. Of the antagonists tested, namely, L-proline, DL-alpha-aminoadipate, DL-2-amino-5-phosphonovalerate, and L-glutamic acid diethyl ester,
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