protease/ניוון ביולוגיה

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Heart Aging When Near Vision Difficulty Begins

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Lens cells and proteins are encapsulated, and they are not turned over or replaced.The lens nucleus starts to form before birth, so the nucleus is one of the three oldest tissues in the body .With aging, continuous cardiomyocyte stress derails proteostasis by causing excessive autophagy and protease

Efficacy of Nafamostat in Covid-19 Patients (RACONA Study)

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Purpose: SARS-Cov-2 enters the lung cells by binding to ACE-2 and activating the protease TMPRSS2, which, therefore, can be a target for antiviral treatment. Accordingly, TMPRSS2 inhibitors prevent SARS-CoV cell entry in vitro. The most potent such inhibitors, nafamostat is being used as

Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

A non-surgical treatment option for the management of osteoarthritis include injectables such as corticosteroids and platelet rich plasma. These injectables work by positively affecting cartilage cells, also known as chondrocytes, and the cells of the joint lining tissue, also known as synoviocytes.

Variability of the Unique Fiber Potentials of a Spastic Muscle Treated With Botulinum Toxin

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Stroke is a frequent, serious and disabling condition. Spasticity interferes with the classic motor pattern and reflects reflex motor activities normally inhibited by the central nervous system. This term most frequently refers to a disorder that causes a speed increase dependent on the tonic

Effectiveness of PENTABIOCEL in Clinical and Laboratory Recovery of Children With Celiac Disease

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Celiac disease (CD) is an intestinal inflammatory condition characterized by permanent intolerance to gluten, a protein complex present in wheat, barley, and rye, in genetically predisposed subjects. In the early phase of the disease, specific autoantibodies are generally present, which is relevant

Evaluation of Outcomes With Amniotic Fluid for Musculoskeletal Conditions Musculoskeletal Conditions

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Medical providers are often faced with patients whose source of pain may be the result of an inflammatory response caused by trauma or disease. By managing the patient's inflammation, the clinician may see improved response to traditional pain management therapy and existing protocols. Also,

Influence of Statins in Artery Aneurysms

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The altered balance between the proteinases and their tissue inhibitors (TIMPS) is one of the pathogenetical mechanism of the aneurysmal connective tissue degeneration. The increase of protease, collagenase and elastase activity results indeed in a dramatic drop of collagen and elastin tissue and

Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Acute muscle wasting occurs early and rapidly during the first week of critical illness and contributes substantially to weakness acquired in the ICU. Muscle wasting and subsequent weakness is associated with delayed liberation from mechanical ventilation, prolonged hospital length of stay (LOS),

Identification of Biochemical and Biomechanical Markers for Cartilage Degeneration in the Knee Joint (IBBM-CKJ)

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Osteoarthritis (OA) is a painful and debilitating disease of the synovial joints, affecting the structural and functional integrity of articular cartilage, subchondral bone, synovium and the adjacent supporting connective tissue . It is a degenerative disorder characterized by cartilage loss with

Oxidative Damage and Antioxidant Mechanisms in COPD

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Introduction Lung is a particularly important organ because of its interface with the environment. The environmental pollutants and endogenous reactive oxygen metabolites from inflammatory cells exert substantial pathological effects on the lung cells [1]. Oxidative stress (OS) is a major factor

Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

3 Background The use of cardiopulmonary bypass (CPB) during cardiac surgery elicits generalized non-specific systemic inflammatory response syndrome (SIRS) and subsequent activation of the cytokine, complement, and coagulation-fibrinolytic cascades (1). In approximately 11% of the patients SIRS may

A Prospective Trial to Identify Biomarkers Involved in the Transition From Acute to Persistent Chronic Low Back Pain

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Investigators will link and relate clinical data to a multiple "omics" analysis in patients developing persistent chronic symptoms (defined as pain that persists 3 months or more), after an episode of acute LBP. The development of persistent chronic pain will be assessed at 3 months after the acute

Platelet-Rich Plasma vs Corticosteroid Injection as Treatment for Degenerative Pathology of the Temporomandibular Joint

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

2.0 OBJECTIVES AND PURPOSE 2.1 The purpose of this study is to compare the efficacy, in terms of pain relief and improvement in function, of intra-articular injections with platelet rich plasma versus the current standard which is corticosteroid injections into the temporomandibular joint.

Effect of Exercise Training on Protein Expression in Skeletal Muscle Tissue After Exercise in Peripheral Arterial Disease

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התחבר הרשם

Why is this clinical problem important? Peripheral Arterial Disease (PAD) is a major health problem in Australia, with a prevalence of 15% in males aged over 65 years. The direct health care cost of PAD in Australia was $180m in 1994, of which 78% was associated with hospitalisations. PAD is also a

Serum and Synovium Protease Inhibitor Levels in Primary and Secondary Osteoarthritic Joints

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

This is a single institution observational study. Pre-procedure diagnosis: Based on chart review and consultation with operating surgeon of subjects undergoing total knee arthroplasty, patients will be grouped into primary or secondary (PTOA) osteoarthritis groups. Primary osteoarthritis will be

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Herbal & Natural Medicine

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