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psoralen/ניוון ביולוגיה

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
עמוד 1 מ 35 תוצאות

Therapeutic effect of psoralen on muscle atrophy induced by tumor necrosis factor-α.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
To observe and determine the effect and mechanism of psoralen on tumor necrosis factor-α (TNF-α)-induced muscle atrophy.Three sets of C2C12 cells, including blank control, TNF-α (10 or 20 ng/ml) treatment and a TNF-α (10 or 20 ng/ml) plus psoralen (80 μM)

Actinic degeneration and pigmentary change in association with psoralen and UVA treatment: a 20-year prospective study.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND Changes in the appearance of the skin including actinic degeneration and pigmentary changes have been noted in patients treated with psoralen and UVA (PUVA). OBJECTIVE Our purpose was to quantify risk factors for increased extent and progression of actinic degeneration and pigmentary

Effects of psoralen on chondrocyte degeneration in lumbar intervertebral disc of rats.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Discuss the internal mechanism of delaying degeneration of lumber intervertebral disc. The cartilage of lumbar intervertebral disc of SD rats was selected in vitro, then cultured by tissue explant method, and identified by HE staining, toluidine blue staining and immunofluorescence. The optimal

Histologic alterations of psoralen- and longwave ultraviolet radiation-exposed skin.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Histologic changes in skin exposed to psoralen photochemotherapy (PUVA) may be classified as acute or chronic. The acute set of histologic alterations includes changes associated with lesion regression and PUVA toxicity. The chronic set of changes related primarily to the side effects of PUVA

Treatment of necrobiosis lipoidica with topical psoralen plus ultraviolet A.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND Necrobiosis lipoidica (NL) is a rare skin disease, mostly seen on the legs and often occurring in patients with diabetes mellitus. The disease belongs to the idiopathic cutaneous palisading granulomatous dermatitides associated with a degeneration of collagen, thus leading to skin

Evaluation of psoralen with solar ultraviolet light (puvasol) and adjunctive topical tar therapy in psoriasis.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Fifty patients having psoriasis were studied with a view to assess the efficacy of 'puvasol' (Oral psoralen with sun-rays exposure) alone and in combination with topical tar therapy and were placed in 2 groups, each group being consisted of 25 patients. At the end of 8 weeks, out of 25 patients

Chronic cutaneous effects of long-term psoralen and ultraviolet radiation therapy in patients with vitiligo.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Vitiligo is refractory to most therapeutic modalities. To assess the efficacy of a variety of PUVA therapies, we enrolled 596 subjects in a prospective study, and 230 were followed for up to 55 months. Various psoralen derivatives and dosage schedules were used. Each subject was examined at yearly

Extracellular granular material and degeneration of keratinocytes in the normally pigmented epidermis of patients with vitiligo.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Multiple biopsy specimens from the skin of 28 patients with common vitiligo were examined by light and electron microscopy. The patients were grouped according to the activity of their disease: progressing, stable, repigmenting, and resistant to treatment with psoralen plus sunlight. Three biopsy

[An experimental study on antitumor activity of psoralen on mammary cancer cell line EMT6 in vitro and in vivo].

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
To investigate the antitumor activity of psoralen on mammary cancer cells of EMT6 line, the cytotoxity of the drug against EMT6 cells was tested by MTT assay; an experimental therapy was carried out in 15 nude mice that were subcutaneously injected with EMT6 cells; the morphological changes of tumor

Antitumor activity of psoralen on mucoepidermoid carcinoma cell line MEC-1.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Psoralen (PSO) was found cytotoxic against in vitro cultured human mucoepidermoid carcinoma cells of MEC-1 cell line. Its IC50 value was 8.6 micrograms/ml, and relative antitumor activity (RAA) 15. PSO suppressed DNA synthesis, damaged microvilli and cell membrane, and induced degeneration of

Intersystem crossing driven by vibronic spin-orbit coupling: a case study on psoralen.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
For 7H-furo[3,2-g][1]benzopyran-7-one (psoralen), intersystem crossing (ISC) rate constants have been computed. Employing the Fermi golden rule, the harmonic approximation, and a pure-spin Born-Oppenheimer basis, both direct and vibronic spin-orbit (SO) coupling has been taken into account.

Psoralen plus UVA vs. UVB-311 nm for the treatment of lichen planus.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND The purpose of this study was to evaluate and compare the short- and long-term therapeutic efficacy of psoralen plus UVA (PUVA) vs. UVB-311 nm in the treatment of patients with disseminated lichen planus. METHODS A computerized data bank search and chart review revealed that data from a

Psoralen stimulates osteoblast differentiation through activation of BMP signaling.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. In order to improve the treatment of osteoporosis, identification of anabolic and orally
Current study examined whether psoralen (PSO) exhibits anti-inflammatory responses, protection and activation of chondrocytes, and relieve osteoarthritis (OA). Rats chondrocytes and human synoviocytes were cultured in tumor necrosis factor-α (TNF-α) conditioned culture medium with/without PSO to

Treatment of oral chronic graft-versus-host disease with PUVA therapy: case report and literature review.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Chronic graft-versus-host disease commonly appears with oral manifestations subsequent to allogeneic bone marrow transplantation. These manifestations include leukoplakia, mucosal atrophy, erythema, ulcers, and xerostomia. Some lesions are resistant to treatment with immunosuppressive medications.
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