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putrescine/השמנת יתר חולנית

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
13 תוצאות

Lower polyamine levels in breast milk of obese mothers compared to mothers with normal body weight.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND Obesity is associated with risks for mother and infant, and the mothers' dietary habits influence breast milk composition. Polyamines are secreted in breast milk and are essential for the regulation of intestinal and immune function in newborns and infants. The present study aimed to

1H NMR-based metabolomic study on resistance to diet-induced obesity in AHNAK knock-out mice.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
AHNAK is a giant protein of approximately 700 kDa identified in human neuroblastomas and skin epithelial cells. Recently, we found that AHNAK knock-out (AHNAK(-/-)) mice have a strong resistance to high-fat diet-induced obesity. In this study, we applied (1)H NMR-based metabolomics with multivariate

Change in serum polyamine metabolome pattern after bariatric surgery in obese patients with metabolic syndrome.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Recent works have reported that bariatric surgery has remarkable effects on the metabolome, which might be potentially associated to the metabolic improvement of this procedure in patients with obesity. Serum polyamines, metabolites derived from amino acid metabolism, have been

Polyamines are increased in obese children and are related to markers of oxidative/nitrosative stress and angiogenesis.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND Polyamines (putrescine, spermidine, and spermine) are polycationic amines derived from arginine, which is the precursor of nitric oxide (NO). Due to the close relationship between the metabolism of polyamines and NO metabolism, the alteration in polyamine homeostasis can affect the NO

Dietary and Gut Microbiota Polyamines in Obesity- and Age-Related Diseases.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The polyamines putrescine, spermidine, and spermine are widely distributed polycationic compounds essential for cellular functions. Intracellular polyamine pools are tightly regulated by a complex regulatory mechanism involving de novo biosynthesis, catabolism, and transport across the plasma
BACKGROUND Gut lactobacilli can affect the metabolic functions of healthy humans. We tested whether a 1500 kcal/d diet supplemented with cheese containing the probiotic Lactobacillus plantarum TENSIA (Deutsche Sammlung für Mikroorganismen, DSM 21380) could reduce some symptoms of metabolic syndrome

Hepatic metabolism of sulfur amino acids in db/db mice.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
To determine the effect of type-2 diabetes and obesity on the hepatic metabolism of sulfur amino acids, hepatic sulfur amino acid metabolism was determined in db/db mice. Hepatic methionine was markedly decreased in db/db mice, although the hepatic activity of betaine homocysteine methyltransferase

Sulfur amino acid metabolism in Zucker diabetic fatty rats.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The present study was aimed to investigate the metabolomics of sulfur amino acids in Zucker diabetic fatty (ZDF) rats, an obese type 2 diabetic animal model. Plasma levels of total cysteine, homocysteine and methionine, but not glutathione (GSH) were markedly decreased in ZDF rats. Hepatic
Alzheimer's disease (AD)-associated sequence (ADAS) of cultured fecal bacteria was discovered in human gut targeted screening. This study provides important information to expand our current understanding of the structure/activity relationship of ADAS and putative inhibitors/activators that are

Gender-Related Differences on Polyamine Metabolome in Liquid Biopsies by a Simple and Sensitive Two-Step Liquid-Liquid Extraction and LC-MS/MS.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Polyamines are involved in the regulation of many cellular functions and are promising biomarkers of numerous physiological conditions. Since the concentrations of these compounds in biological fluids are low, sample extraction is one of the most critical steps of their analysis. Here, we developed

Impact of probiotic feeding during weaning on the serum lipid profile and plasma metabolome in infants.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The gut microbiome interacts with the host in the metabolic response to diet, and early microbial aberrancies may be linked to the development of obesity and metabolic disorders later in life. Probiotics have been proposed to affect metabolic programming and blood lipid levels, although studies are

Experimental bariatric surgery in rats generates a cytotoxic chemical environment in the gut contents.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Bariatric surgery, also known as metabolic surgery, is an effective treatment for morbid obesity, which also offers pronounced metabolic effects including the resolution of type 2 diabetes and a decrease in cardiovascular disease and long-term cancer risk. However, the mechanisms of surgical weight

Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
OBJECTIVE Bariatric surgery is increasingly performed worldwide to treat morbid obesity and is also known as metabolic surgery to reflect its beneficial metabolic effects especially with respect to improvement in type 2 diabetes. Understanding surgical weight loss mechanisms and metabolic modulation
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