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pyridine/hypoxia

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
עמוד 1 מ 129 תוצאות

Permeability transition pore-dependent and PARP-mediated depletion of neuronal pyridine nucleotides during anoxia and glucose deprivation.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Exposure of rat cortical neurons to combined oxygen and glucose deprivation results in loss of NAD(P)H autofluorescence that is only partially reversible following restoration of oxygen and glucose, suggesting catabolism of pyridine nucleotides. This study tested the hypothesis that metabolic

[Pyridine nucleotide content in the brain and myocardium of rats under combined effect of hypercapnia, hypoxia and cooling].

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
In experiments with rats, subjected to single and repeated simultaneous effect of hypercapnia, hypoxia and cooling, contents of pyridine nucleotides (NAD, NADP, NAD-H2 and NADP-H2) and macroergic substances were studied and also the activity of dehydrogenases of the pentose pathway was determined in

Pyridine nucleotides of rabbit cornea with histotoxic anoxia: chemical analysis, non-invasive fluorometry and physiological correlates.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The pyridine nucleotides from both the epithelium and the endothelium of rabbit cornea were measured by the cycling assay. Sodium azide (10 mM) applied for 1 hr to induce histotoxic anoxia decreased the endothelial NAD+/NADH ratio from 4.62 to 1.49 and decreased the epithelial NAD+/NADH ratio from

Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
2-Nitroimidazoles, such as pimonidazole, are reduced in cells with low oxygen tension and are, therefore, used as hypoxia markers. However, the effect of the pyridine nucleotide redox state on pimonidazole reduction is not known. Therefore, livers from fed or fasted rats were perfused with
Pyridine nucleotide fluorescence made from the surface of the hemoglobin-free perfused rat liver was measured continuously by using a "micro-light guide" placed on selected periportal and pericentral regions of the liver lobule. From the portal oxygen tension at which pyridine nucleotide reduction

Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
NAD(P)H autofluorescence was used to verify establishment of metabolic anoxia using primary cultures of cortical neurons and astrocytes. Cells on cover slips were placed in a chamber and O(2) was displaced by continuous infusion of argon. Perfusion with medium at PO(2) < 0.4 mm Hg caused an increase

[Effect of certain water-soluble vitamins on the pyridine coenzyme content of animal tissues under conditions of hypoxia].

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם

[Content of pyridine nucleotides and some metabolites in rat kidney cortex during normal oxygen tension and anoxia].

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם

Selective modulation of membrane currents by hypoxia in intact airway chemoreceptors from neonatal rabbit.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
1. We previously described voltage-dependent ionic currents and hypoxia chemosensitivity in cultured pulmonary neuroepithelial body (NEB) cells isolated from fetal rabbit. Here we use fresh neonatal rabbit lung slices (200-400 micrometer thick) to characterize the electrophysiological properties of

Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Aromatic analogues of the 2-oxoglutarate co-substrate of the hypoxia-inducible factor hydroxylases are shown to bind at the active site iron: Pyridine-2,4-dicarboxylate binds as anticipated with a single molecule chelating the iron in a bidentate manner. The binding mode of a hydroxamic acid

Pyridine nucleotide as an indicator of the oxygen requirements for energy-linked functions of mitochondria.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The responses of cardiac mitochondria to anoxia may be evaluated in terms of the oxidation-reduction state of the electron carriers and the ability of the mitochondria to function in energy-linked reactions. The previous detailed evaluation of the oxygen requirements for electron transfer in
A special "anoxia test" was developed with isolated guinea pig atria to test influences on the anoxic energy balance. Adenine, ribose, nicotinic acid or nicotinamide added as precursors to nutrition solutions inhibit the loss of cardiac adenine and pyridine nucleotides during anoxia and improve the
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