15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min

Periodontal Diseases

Distilled water

Hayder R Abdulbaqi

Anti Plaque Efficacy of Salvadora Persica L. and Green Tea Mouthwash

Evaluation of Anti-plaque Effect of a Mouthwash Composed of Salvadora Persica L. and Green Tea: a 4days Randomized Controlled Crossover Clinical Trial

Mean amount plaque between different comparators as anti-plaque agent following 24 hrs plaque regrowth clinical trial by means of modified quigely hein plaque index [Turesky, 1970] and digital plaque image analysis.

Mean amount plaque between different comparators as anti-plaque agent following 4 days plaque regrowth clinical trial by means of modified quigely hein plaque index [Turesky, 1970] and digital plaque image analysis.

Mean bacterial load in saliva at 2 hours after rinsing with different comparators using quantitative polymerase chain reaction (qPCR).

Mean relative changes in gingival crevicular fluid flow rate after rinsing with different comparators from baseline at 4 days.

Mean relative changes in Interleukin1 beta levels in gingival crevicular fluid after rinsing with different comparators from baseline at 4 days.

Hayder Raad Abdulbaqi

Principal Investigator

University of Baghdad

The group contains healthy individuals with chronic periodontitis who will receive Normal Saline as placebo

The group contains healthy individuals with chronic periodontitis who will receive Nigella sativa Oil as intervention

Chronic Periodontitis

The individuals will apply 55 drops of Nigella sativa Oil on gingivae twice daily for two weeks

Nigella Sativa Oil

The individuals will apply 55 drops of Normal saline on gingivae twice daily for two weeks

Normal saline

Fatima Memorial Hospital

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis Before and After Treatment With Nigella Sativa (Kalonji) Oil

These inflammatory marker will be measured in patients saliva again after 2 weeks. There will be reduction in their levels.

Data sharing will be considered after the completion of studies

Dr. Ghazala Hassan

Research Scholar

University of Health Sciences Lahore

Healthy Individuals with Chronic Periodontitis Only

Healthy Volunteers

15ml DTC1 twice a day, rinse for 30sec refrain from eating or drinking for 30min

DTC1

15ml Chlorhexidine gluconate 0.12% (w/v) twice a day, rinse for 30sec refrain from eating or drinking for 30min

Oradex

15ml distilled water twice a day, rinse for 30sec refrain from eating or drinking for 30min

salvadora persica/אנטי בקטריאלי

Anti Plaque Efficacy of Salvadora Persica L. and Green Tea Mouthwash

Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis

Evaluation of Synergistic Anti-plaque Activity of Salvadora Persica L. and Green Tea: A Clinical Comparative Study

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע