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saponaria officinalis/אנטי פטרייתי

הקישור נשמר בלוח
מאמריםניסויים קלינייםפטנטים
עמוד 1 מ 18 תוצאות

HER/erbB receptors as therapeutic targets of immunotoxins in human rhabdomyosarcoma cells.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Human rhabdomyosarcoma cells express HER/erbB growth factors receptors. Receptors belonging to this family are overexpressed and play a role in many types of epithelial and neural cancer and have been selected as targets for cancer therapy. In this paper EGF-R, HER-2 and HER-3 receptors were tested

Enzymatic specificity of three ribosome-inactivating proteins against fungal ribosomes, and correlation with antifungal activity.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Ribosome-inactivating proteins (RIPs) are enzymes that cleave a specific adenine base from the highly conserved sarcin/ricin (S/R) loop of the large ribosomal RNA, thus arresting protein synthesis at the translocation step. In the present study, we employed three RIPs to dissect the antifungal

Bioproduction of a Therapeutic Vaccine Against Human Papillomavirus in Tomato Hairy Root Cultures.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Human papillomavirus (HPV) tumor disease is a critical public health problem worldwide, especially in the developing countries. The recognized pathogenic function of E5, E6, and E7 oncoproteins offers the opportunity to devise therapeutic vaccines based on engineered recombinant proteins. The

Antifungal activity of the extracts and saponins from Sapindus saponaria L.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Extracts from the dried pericarp of Sapindus saponaria L. (Sapindaceae) fruits were investigated for their antifungal activity against clinical isolates of yeasts Candida albicans and C. non-albicans from vaginal secretions of women with Vulvovaginal Candidiasis. Four clinical isolates of C.

Biodegradation of clotrimazole and modification of cell properties after metabolic stress and upon addition of saponins.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Azole fungicides constitute an extensive group of potential emerging pollutants which can be found in natural environment. This study focuses on the biodegradation of clotrimazole and the characterization of cell surface properties of microorganisms capable of degradation of this compound. The

Saporin 6 conjugated to monoclonal antibody selectively kills human melanoma cells.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
A novel human melanoma specific immunotoxin is described, which has been produced utilizing the murine monoclonal antibody (mAb) Ep2, IgG2a isotype, recognizing an epitope of the glycoprotein/proteoglycan high molecular weight-melanoma associated antigen. mAb Ep2 has been chemically conjugated by a

Macromolecular interactions of triterpenoids and targeted toxins: role of saponins charge.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Macromolecular interaction of protein toxins with certain plant triterpenoids holds potential for application in tumor therapy. The ability of only certain saponins to enhance the endosomal escape of toxins specifically in tumor cells was evaluated and set into correlation with the electrophoretic

Saponins from Saponaria officinalis L. Augment the Efficacy of a Rituximab-Immunotoxin.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Triterpenoidal saponins are synthesized in the roots of Saponaria officinalis L. The same plant is also a source for the toxin Saporin, which is a ribosome-inactivating protein. Triterpenoidal saponins are known to increase the cytotoxicity of Saporin by modulating its intracellular trafficking.

New pharmacological properties of Medicago sativa and Saponaria officinalis saponin-rich fractions addressed to Candida albicans.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The antifungal activity of the saponin-rich fractions (SFs) from Medicago sativa (aerial parts and roots) and Saponaria officinalis (used as a well-known source of plant saponins) against Candida albicans reference and clinical strains, their yeast-to-hyphal conversion, adhesion, and biofilm

In vivo activity of Sapindus saponaria against azole-susceptible and -resistant human vaginal Candida species.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
BACKGROUND Study of in vivo antifungal activity of the hydroalcoholic extract (HE) and n-BuOH extract (BUTE) of Sapindus saponaria against azole-susceptible and -resistant human vaginal Candida spp. METHODS The in vitro antifungal activity of HE, BUTE, fluconazole (FLU), and itraconazole (ITRA) was

In vitro evaluation and molecular docking of QS-21 and quillaic acid from Quillaja saponaria Molina as gastric cancer agents

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
The cytotoxic mechanism of the saponin QS-21 and its aglycone quillaic acid (QA) was studied on human gastric cancer cells (SNU1 and KATO III). Both compounds showed in vitro cytotoxic activity with IC50 values: 7.1 μM (QS-21) and 13.6 μM (QA) on SNU1 cells; 7.4 μM (QS-21) and 67 μM (QA)

Cellular Structural Changes in Candida albicans Caused by the Hydroalcoholic Extract from Sapindus saponaria L.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Vulvovaginal candidiasis (VVC) is a disease caused by the abnormal growth of yeast-like fungi in the mucosa of the female genital tract. Candida albicans is the principal etiological agent involved in VVC, but reports have shown an increase in the prevalence of Candida non-C. albicans (CNCA) cases,

Saponins from Quillaja saponaria and Quillaja brasiliensis: Particular Chemical Characteristics and Biological Activities.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Quillaja saponaria Molina represents the main source of saponins for industrial applications. Q. saponaria triterpenoids have been studied for more than four decades and their relevance is due to their biological activities, especially as a vaccine adjuvant and immunostimulant, which

Altered immunomodulating and toxicological properties of degraded Quillaja saponaria Molina saponins.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Quillaja saponins are readily hydrolyzed under physiological conditions, yielding deacylated forms that are significantly less toxic than their precursors. Yet, deacylated saponins are unable to stimulate a strong primary immune response. Although deacylated saponins elicit a strong total IgG

Immunotoxins, ligand-toxin conjugates and molecular targeting.

רק משתמשים רשומים יכולים לתרגם מאמרים
התחבר הרשם
Biotechnology provides tools for therapeutic exploitation following advances in the elucidation of protein-to-cell and cell-to-cell interactions. Molecular targeting of bacterial and plant toxins to the desired district of action can be achieved through effector molecules like monoclonal antibodies
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