In this group, the patients received 100mg ferrous succinate and 200mg vitamin C three times per day for 3-4 months

In this group, the patients received 100mg ferrous succinate three times per day for 3-4 months

In this group, the patients received 200mg ferrous succinate three times per day for 3-4 months

Anemia, Iron-Deficiency

As experimental group, when patients take the tablets of ferrous succinate, they also take vitamin C at the same time

ferrous succinate and vitamin C

As active comparator, patients take the tablets of ferrous succinate with normal dosage in clinical practice

ferrous succinate

As another active comparator, patients take the tablets of ferrous succinate with double dosage

Hushan Hospital

the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients

The Efficacy and Safety of Vitamin C for Iron Supplementation Therapy in Adult Patients With Iron Deficiency Anemia(IDA)

The increased levels of hemoglobin after receiving three different treatment regimens are evaluated in the second week

The increased levels of reticulocyte after receiving three different treatment regimens are evaluated in the second week

The increased levels of hemoglobin after receiving three different treatment regimens are evaluated in the fourth week

The increased levels of ferritin after receiving three different treatment regimens are evaluated in the eighth week

The incidence of adverse events every two weeks are assessed, the adverse events include bellyache, diarrhea, constipation, vomiting, nausea.

xiao-qin wang

professor

Huashan Hospital

Patients with a positive lactose-breath test and complaints during the test

Patients with a positive lactose-breath test and no complaints during the test

Subjects with a negative lactose-breath test

Lactose Intolerance

TARGID, KU Leuven

Comparison of the Colonic Metabolism in Patients With Lactose Intolerance and Healthy Controls

Fecal water, prepared by ultracentrifugation of fecal samples, will be incubated with HT-29 cells, a colonic adenocarcinoma cell line. Fecal water genotoxicity will be assessed using the Comet Assay, a sensitive method to detect DNA damage at the level of the individual eukaryotic cell. During the Comet Assay, the cells undergo electrophoresis causing movement of the damaged DNA out of the nucleus. The amount of DNA damage will be determined by measuring the extent the DNA has moved out of the nucleus, using fluorescent microcropy and dedicated software.

Fecal water cytotoxicity will be measured using the WST-1 assay, a colorimetric test based on the conversion of the tetrazolium salt WST-1 by cellular mitochondrial dehydrogenases present in viable cells. The dilution of fecal water at which 50% of the cells survive will be determined. The higher the dilution, the more cytotoxic the sample is.

succinate/שלשול

the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients

Comparison of the Colonic Metabolism in Patients With Lactose Intolerance and Healthy Controls

המאגר השלם ביותר של צמחי מרפא המגובה על ידי המדע