taxus brevifolia/סרטן השד

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Docetaxel: a new active agent in the therapy of metastatic breast cancer.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Breast cancer is the most common malignancy in women, accounting for about 18% of female cancers, and over half a million new cases are diagnosed worldwide each year. Its incidence increases with age and is currently rising. Although the increased availability of screening programs has allowed

Paclitaxel in breast cancer.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel, a chemotherapeutic drug isolated from the Pacific yew, was approved for the treatment of metastatic breast cancer in 1994 and remains one of the most important agents in the treatment of patients with this disease. It is currently approved for the adjuvant treatment of node-positive

Ixabepilone and other epothilones: microtubule-targeting agents for metastatic breast cancer.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Taxanes, derived from the bark of the Pacific yew tree, were the last major group of cytotoxic agents to be developed. Their proven efficacy in a variety of malignancies has constituted a real breakthrough in the treatment of cancer. Wider clinical use of taxanes has several important limitations,

[Taxol--a new cytostatic drug for therapy of ovarian and breast cancer].

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Taxol is a cytostatic agent of plant origin with a complex structure and a special mode of action. Owing to the small content of this substance in the bark of the Pacific yew, from which Taxol is derived, it has only been available on a limited scale. Hitherto, Taxol's chemical structure has

Taxanes in adjuvant and neoadjuvant therapies for breast cancer.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel (Taxol) is a diterpene originally obtained from the bark of the Pacific Yew Tree, Taxus Brevifolia. Its mechanism of action is unique. It stabilizes microtubule polymerization, thus blocking cells in the G2/M phase of the cell cycle. In breast cancer, initial studies using paclitaxel

Docetaxel-induced Scleroderma in A Breast Cancer Patient: A Case Report.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel and docetaxel are antineoplastic drugs derived from the yew tree, Taxus brevifolia. They are the members of the taxane family and act by inhibiting mitotic activity due to the suppression of microtubule depolymerization. They are used in the treatment of ovarian cancer, breast cancer,

Paclitaxel (Taxol) in breast cancer.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel (Taxol) is a diterpine plant compound that was isolated initially from the bark of the western yew tree, Taxus brevifolia, but can now be produced by semisynthesis from a renewable source. Paclitaxel is the first new agent in the past decade to have confirmed single agent activity in

Paclitaxel suppresses the viability of breast tumor MCF7 cells through the regulation of EF1α and FOXO3a by AMPK signaling.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel (Taxol), a potent drug of natural origin isolated from the bark of the Pacific yew, is widely used for treating ovarian, lung and breast cancers. Currently, there is little information regarding the specific mechanism underlying the anticancer activity of paclitaxel. In the present study,

A phase I trial of 3-hour infusions of paclitaxel (Taxol) with or without granulocyte colony-stimulating factor.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ), a novel antitubulin agent derived from the bark of the Pacific yew tree, may be one of the most active single agents in our chemotherapy armamentarium. Concern over acute hypersensitivity reactions has resulted in an administration

Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing water-soluble prodrugs of paclitaxel.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel (Taxol) is a diterpenoid isolated from Taxus brevifolia, used clinically for the treatment of ovarian and breast cancer. Due to its aqueous insolubility it is administered dissolved in ethanol and Cremophor EL (polyethoxylated castor oil), which has serious side effects. In order to

Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel is a diterpenoid isolated from Taxus brevifolia. It is effective for various cancers, especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered dissolved in ethanol and Cremophor EL (BASF, Ludwigshafen, Germany), which can cause serious allergic reactions.

[Pharmacological action of paclitaxel].

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel (taxol, Tax) is a novel plant product isolated from the Pacific yew (Taxus brevifolia). It has a unique mechanism of action, because it induces very stable and dysfunctional microtubules. Paclitaxel has a broad spectrum of antineoplastic activity. It has been successfully used in the

Paclitaxel: a new antimitotic chemotherapeutic agent.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Paclitaxel, a compound derived from the bark of the Pacific yew, Taxus brevifolia, is an antimitotic cytotoxic agent with a mechanism of action different from other antimitotics such as vincristine and vinblastine. Instead of causing disassembly of microtubules, paclitaxel forms extremely stable and

Phase I study of escalating doses of paclitaxel (Taxol) with fixed doses of ifosfamide, carboplatin, and etoposide.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

The combination of ifosfamide (with mesna uroprotection), carboplatin, and etoposide (ICE) has demonstrated activity in a variety of cancers. Paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ), a dipertene compound extracted from the Pacific yew Taxus brevifolia, appeared a good

Anticancer activity of fungal taxol derived from Botryodiplodia theobromae Pat., an endophytic fungus, against 7, 12 dimethyl benz(a)anthracene (DMBA)-induced mammary gland carcinogenesis in Sprague Dawley rats.

רק משתמשים רשומים יכולים לתרגם מאמרים

התחבר הרשם

Breast cancer is the second most prevalent cancer worldwide and their incidence increases gradually. Taxol (paclitaxel), a potent anticancer drug, is naturally isolated from the bark of the Pacific yew. Taxol is widely used in the treatment of ovarian, lung and breast cancer. The increased demand

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