[Early morphologic changes in the myocardium after a wound of the heart complicated by hemopericardium (experimental study)].

The myocardia of 20 dogs with penetrating injuries of the right ventricles were studied morphologically and histochemically. Microcirculatory disorders found in the myocardium included overfilled venous and capillary bed that eventually led to capillary stasis, interstitial edema, hemorrhagic foci, arteriolosclerosis. For the first time focal disseminated injuries of cardiomyocytes of a segmental, zonal, and contractural type were detected. In line with these lesions, earlier cardiomyocytic changes were found, such as margination of nuclear chromatin, clarification of karyoplasm, interfibrillar edema of sarcoplasm with subsequent loosening and aggregation of myofibrils. This complex of morphologic changes was invariably found in the myocardia of both ventricles in the dogs dead 10-90 minutes after cardiac injury.