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Archives of Physiology and Biochemistry 2011-Dec

Relationship of dyslipidemia and uric acid with the risk of myocardial infarction among hypertensive patients in Trinidad.

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B Shivananda Nayak
Nalini Maharaj
Satish S Maharaj
Kyle Evernden
Unoda Fane
Le-Ann Lue Fatt
Dev Maharaj
Samera Maharaj
Varsha Maharaj
Victoria Maloney

キーワード

概要

OBJECTIVE

To study the relationship of dyslipidemia and serum uric acid with the risk of myocardial infarction among the hypertensive type 2 diabetic and non-diabetic patients of Trinidad.

METHODS

Data were obtained from the hospital records of 672 adults who were treated for hypertension in public health clinics in Trinidad.

RESULTS

The prevalence of myocardial infarction was 25.45% in the sample. Males accounted for 52.63% while females accounted for 47.37%. Hypertensive type 2 diabetics with dyslipidemia had greater occurrence of MI (23.93%) than non-diabetic hypertensive patients (7.67%) (p=0.008). Useful predictors of MI included: diabetes mellitus, altered lipid profile, family history of any cardiac conditions. On further analysis, hypertension class (p=0.003) and serum uric acid quartile (p=0.029) were also significant predictors of MI.

CONCLUSIONS

The results suggest that there is a greater prevalence of MI in hypertensive type 2 diabetic patients with dyslipidemia than in non-diabetic hypertensive patients in Trinidad.

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