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Indian Journal of Otolaryngology and Head and Neck Surgery 2000-Jul

Role of ginkgo biloba extract in acquired sensorineural hearing loss.

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A Kumar
R M Raizada
V N Chaturvedi

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概要

The present study is on 52 patient of acquired SNHL who were treated with Ginkgo biloba extract (Ginkocer) or conventional treatment (Neurobion, Arlidine & Vit -A) or both. The age range was 11-75 years with male: female - 3.1. Commonest probable etiology was presbyacusis (36.5%) followed by idiopathic (28.8%). Subjective improvement in hearing was comparable in both the ttreatment groups. Objective improvement (> 10 dB ) was seen with Ginkocer therapy only in cases of idiopathic (3). ototoxicity (1) head injury (1). It was maximum in <25 yrs. age and ranged between 11-50 dB. However, statistically it was not significant for age, sex, socioeconomic status, oral habits, Hb level, serum cholesterol and albumin: globulin ratio. Patients showing no effect of drug were almost comparable in both the groups. In conventional group the remaining patients demonstrated drug efficacy of 30% while in the Ginkocer group it was upto 60%. The mean improvement in tinnitus was 52.32% with Ginkocer and 50.09% with conventional treatment. Relative improvement with Ginkocer was found better by 15.56%, 21.94% & 9.09% in presbyacusis, idiopathic: and ototoxicity group as compared to conventional group.

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