Bioorganic and Medicinal Chemistry Letters 2011-Jan
The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists.
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概要
The discovery and structure-activity relationship of a novel series of indole-2-carboxamide antagonists of the cannabinoid CB(1) receptor is disclosed. Compound 26i was found to be a high potency, selective cannabinoid CB(1) antagonist.