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amide/アサ属

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7 結果

Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase for modulation of cannabinoid receptors

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FIELD OF THE INVENTION The present disclosure relates generally to the fields of medicinal chemistry and receptor biology. More particularly, the disclosure relates to the use of certain chemical compounds in methods for treating pain, inflammation, neuropathy, neurodegenerative disease, anxiety

N-[(4,5-diphenyl-3-alkyl-2-thienyl)methyl]amine [amide, sulfonamide, carbamate and urea) derivatives as cannabinoid CB1 receptor antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to substituted N-[(4,5-diphenyl-3-alkyl-2-thienyl)methyl]amine derivatives, to their preparation and to their therapeutic use. 2. Description of the Art Diphenylpyrazole derivatives with affinity for the cannabinoid

Diphenyl cyclopentyl amides as cannabinoid-1 receptor inverse agonists

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BACKGROUND OF THE INVENTION Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research

Therapeutic use of mono and bicarboxylic acid amides active at the peripheral cannabinoid receptor

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FIELD OF THE INVENTION The present invention relates to a therapeutic method for the treatment of diseases connected with the modulation of the cannabinoid peripheral receptor, comprising administering amidic derivatives of mono and bicarboxylic acids with substituted aminoalcohols or

Substituted N-phenyl-5-phenyl-pyrazolin-3-yl amides as cannabinoid receptor antagonists/inverse agonists useful for treating obesity

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FIELD OF THE INVENTION The present invention provides novel substituted N-phenyl-5-phenyl-pyrazolin-2-yl amides and derivatives thereof as cannabinoid receptor antagonists/inverse agonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes,

Crystalline forms and processes for the preparation of cannabinoid receptor modulators

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FIELD OF THE INVENTION The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclop- ropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that

Crystalline forms and processes for the preparation of cannabinoid receptor modulators

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FIELD OF THE INVENTION The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclop- ropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that
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