anti allergic/fever

The efficacy of the new anti-allergic compound oxatimide was tested in a double-blind study against a placebo during the pollen season of 1976 in 215 patients (4 1/2--69 years) with hay fever. Adult patients were instructed to take two tablets (= 20 mg) three times a day for 2 weeks, children

OBJECTIVE To evaluate the efficacy and safety of immunotherapy (hyposensitisation) in patients with severe summer hay fever. METHODS A randomised, double blind, placebo controlled study of a biologically standardised depot grass pollen extract. METHODS Allergy clinic, Royal Brompton and National

This enquiry covers 2961 active Swiss athletes of national or international standing in 68 different sports. Of these, 2060 (70%; 1507 males, 552 females) answered the questionnaire. 347 athletes (16.8%) indicated they suffered from hay fever, 204 of them (59%) needing medication during the pollen

Nasal histamine provocation was performed in ll asymptomatic (out of season) patients with hay fever and in ll normal controls. Posterior rhinomanometry was used for objective evaluation. The histamine challenges caused nasal symptoms as well as increased nasal airway resistance. The differences in

Beta-adrenergic agents have a direct relaxing effect on bronchial smooth muscle. In vitro investigations of a number of sensitized preparations have demonstrated an inhibition of the antigen-induced histamine release. Grass pollen allergic patients were pretreated in the laboratory, out of the

A clinical course of pulmonary tuberculosis was reported about adverse reaction of anti-tuberculous chemotherapy. A fifty-eight-year-old male patient was complicated with agranulocytosis induced by RFP, hepatic dysfunction and systemic eruption induced by INH, and high fever induced by SM. Adjuvant

Nasal spray from lemon and quince (LQNS) is used to treat hay fever symptoms and has been shown to inhibit histamine release from mast cells in vitro. Forty-three patients with grass pollen allergy (GPA) were randomized to be treated either with placebo or LQNS for one week, respectively, in a

In a group of 55 allergic patients with hay fever, and including patients treated by complete placebo, the action of Lorazepam has been studied from both the psycho-somatic and the allergic point of view. This most obviously allergic of all allergic diseases has been especially chosen because it was

The effects of the novel antiasthmatic/antiallergic compound flezelastine on LPS-induced actions were investigated in vitro and in vivo. In monocytes, IL-1 beta generation stimulated by LPS was inhibited dose dependently. In vivo, LPS-induced fever in rats, which is at least partly driven by the

Ragweed pollinosis was first described in the middle Rhône valley in the early sixties. Prevalence has increased steadily since that time. The aim of the present study was to determine whether this phenomenon is perceptible in terms of anti-allergic drug sales (eye drops, nasal spray, oral

BACKGROUND Many people suffer from hay fever symptoms. Hypnosis has proved to be a useful adjunct in the treatment of conditions where allergic phenomena have an important role. METHODS Randomised parallel group study over an observation period of two consecutive pollen seasons. Outcome data include

Familial Mediterranean fever (FMF) is an inherited inflammatory disease occurring mainly in Mediterranean and Middle Eastern populations. FMF is caused by mutations in the MEFV gene that encodes pyrin/marenostrin. Here, we report a Japanese female FMF patient with heterozygosity for the compound

Leukotrienes (LTs), chemical mediators produced by mast cells, play an important role in allergic symptoms such as food allergies and hay fever. We tried to construct an evaluation method for the anti-LTB4 activity of chemical substances using a mast cell line, PB-3c. PB-3c pre-cultured with or

Using a panel of chemical, biochemical, and cell assays, we determined inhibitory effects of extracts of the pigmented black rice brans on in vitro allergic reactions. Ethanol-water (70% v/v) extracts from 5 pigmented brans were found to be more effective than an extract from a nonpigmented rice