antiasthmatic/hepatitis

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Muscle-strengthening drugs and anti-inflammatory drugs

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TECHNICAL FIELD The present invention relates to a novel agent or composition for use as a muscle-strengthening drug, an anti-inflammatory drug, an antiasthmatic, an antidiarrheal, an antidepressant, or a drug for the treatment of secondary diseases following cerebral infarction (human stroke

Indole carbamates as leukotriene antagonists

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BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes are Leukotriene B.sub.4 (abbreviated at LTB.sub.4), LTC.sub.4, LTD.sub.4 and LTE.sub.4. The biosynthesis of these leukotrienes begins

1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes are Leukotriene B.sub.4 (abbreviated as LTB.sub.4), LTC.sub.4, LTD.sub.4 and LTE.sub.4. The biosynthesis of these leukotrienes begins

Aryl thiopyrano[4,3,2-cd]indoles as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes are Leukotriene B.sub.4 (abbreviated as LTB.sub.4), LTC.sub.4, LTD.sub.4, and LTE.sub.4. The biosynthesis of these leukotrienes begins

Thiopyrano[2,3,4-c,d]indoles as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes are Leukotriene B.sub.4 (abbreviated as LTB.sub.4), LTC.sub.4, LTD.sub.4 and LTE.sub.4. The biosynthesis of these leukotrienes begins

Pyrrolo[1,2-a]indole hydroxylamine derivatives as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes areLeukotriene B.sub.4 (abbreviated at LTB.sub.4), LTC.sub.4, LTD.sub.4 and LTE.sub.4. The biosynthesis of these leukotrienes begins

Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis

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Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes are Leukotriene B.sub.4 (abbreviated as LTB.sub.4), LTC.sub.4, LTD.sub.4, and LTE.sub.4. The biosynthesis of these leukotrienes begins

Furo[3,2-b]pyridines and thieno[3,2-b]pyridines as inhibitors of leukotriene biosynthesis

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CROSS-REFERENCE The compounds of formula I' are described in U.S. Ser. No. 951,630, filed Sep. 25, 1992 now U.S. Pat. No. 4,308,850. BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and

Pyridine-substituted benzyl alcohols as leukotriene antagonists

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BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes are Leukotriene B.sub.4 (abbreviated at LTB.sub.4), LTC.sub.4, LTD.sub.4, and LTE.sub.4. The biosynthesis of these leukotrienes begins

Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis

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CROSS-REFERENCE The hydroxyacid forms of the present lactones are the subject of a U.S. patent application, attorney docket no. 18761, U.S. Ser. No. 07/936,810, now U.S. Pat. No. 5,252,599, filed on even date herewith, which is incorporated herein by reference. BACKGROUND OF THE INVENTION The

Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis

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CROSS-REFERENCE The hydroxyacid forms of the present lactones are the subject of a co-pending U.S. patent application, attorney docket no. 18812, Ser. No. 07/936,811, filed on even date herewith, which is incorporated herein by reference. BACKGROUND OF THE INVENTION The leukotrienes constitute a

Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis

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The hydroxyacid forms of the present lactones are the subject of a co-pending U.S. patent application U.S. Ser. No. 834,912, filed on even date herewith, which is incorporated herein by reference. BACKGROUND OF THE INVENTION The leukotrienes constitute a group of locally acting hormones, produced in

Heteroaryl coumarins as inhibitors of leukotriene biosynthesis

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BACKGROUND The leukotrienes constitute a group of locally acting hormones, produced in living systems from arachidonic acid. The major leukotrienes are Leukotriene B.sub.4 (abbreviated as LTB.sub.4), LTC.sub.4, LTD.sub.4, and LTE.sub.4. The biosynthesis of these leukotrienes begins with the action

Quinoline leukotriene antagonists

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BACKGROUND OF THE INVENTION U.S. Pat. No. 5,565,473 discloses the compound of the formula (a): ##STR2## now generally known as montelukast sodium. Montelukast sodium is a leukotriene antagonist and is currently undergoing clinical trials for the treatment of chronic asthma. PCT Published Application

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