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5 結果
2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives
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FIELD OF THE INVENTION
This invention provides benzoic acid and amide derivatives of anthranilic acids which inhibit certain dual specificity kinase enzymes involved in proliferative diseases such as cancer and restenosis.
BACKGROUND OF THE INVENTION
Proliferative diseases are caused by a defect in
2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives
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FIELD OF THE INVENTION
This invention provides benzoic acid and amide derivatives of anthranilic acids which inhibit certain dual specificity kinase enzymes involved in proliferative diseases such as cancer and restenosis.
BACKGROUND OF THE INVENTION
Proliferative diseases are caused by a defect in
2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors
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FIELD OF THE INVENTION
This invention provides benzoic acid and amide derivatives of anthranilic acids which inhibit certain dual specificity kinase enzymes involved in proliferative diseases such as cancer and restenosis.
BACKGROUND OF THE INVENTION
Proliferative diseases are caused by a defect in
Novel benzoic and phenylacetic acid derivatives
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SUMMARY OF THE INVENTION
The present invention relates to novel benzoic acid and phenylacetic acid derivatives, a process for their manufacture, pharmaceutical preparations which contain such compounds as well as the use of these compounds in the manufacture of pharmaceutical preparations.
DETAILED
Pyridine alkyl benzoic and thenoic acid compounds and their pharmaceutical compositions
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This invention relates to pyridine derivatives, to processes for their preparation and to pharmaceutical compositions containing them.
Up to now, of the compounds having a pyridine skeleton, it has been reported that 2-isopropyl-3-nicotinylindole(L-8027) possesses an inhibitory activity on
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