10 結果
The purpose of this study is to determine the immune response from the new Shingrix vaccine in UC patients on tofacitinib monotherapy in comparison to other UC therapies. the investigators plan to determine this by vaccinating IBD patients on (a) tofacitinib monotherapy, (b) anti-TNF monotherapy,
A lower respiratory tract infection is a serious situation that can abruptly become complicated by sepsis, respiratory failure, lung tissue necrosis, and multiple organ dysfunction. Hence, empiric antibiotic treatment is commonly initiated as soon as infection is suspected and cultures and/or other
Cholangiocarcinoma and pancreatic cancer are by far the two most common causes of malignant bile duct obstruction. Cholangiocarcinoma is an adenocarcinoma originating in the bile duct whereas pancreatic cancer is an adenocarcinoma derived from pancreatic ductal cells. The incidence rates of both
Japanese encephalitis (JE) is the most important epidemic encephalitis worldwide, causing approximately 35-50,000 cases and 10-15,000 deaths annually. Half of the survivors have severe neuropsychiatric sequelae, posing a large socio-economic burden on communities that can ill afford it. JE virus
Detailed Description of Study Evaluations
Adherence to treatment evaluation:
Patients will be asked to bring the empty packages of the IFN beta and Vitamin D that were used during the study.
Flu like symptoms and Injection site reactions evaluation:
Data regarding FLS and ISRs will be collected by
Both methotrexate and adalimumab are FDA-approved drugs for the treatment of moderate to severe psoriasis. The two treatments, methotrexate and adalimumab, both show efficacy for psoriasis, however their profiles differ. In the CHAMPION Study, more adalimumab-treated, moderate to severe psoriasis
Method of Harvesting Stem Cells
Based on the experience of the pilot studies, the current protocol will mobilize stem cells with granulocyte-colony stimulating factor (G-CSF) and collect stem cells by apheresis, with subsequent bone marrow harvest performed only if needed to supplement the
Selection of the Regimen for Immunosuppressive Therapy
Cyclophosphamide with ATG is a common conditioning regimen with two decades of experience in the treatment of aplastic anemia, and has been used safely without reported mortality in the treatment of autoimmune diseases such as systemic lupus
Selection of High Dose Immunosuppressive Therapy and Autologous HSCT Strategy for this Trial
Selection of the Regimen for High-Dose Immunosuppressive Therapy Cyclophosphamide with ATG (Cy/ATG) is a common conditioning regimen with two decades of experience in the treatment of aplastic anemia and has
BACKGROUND:
- Lymphomatoid granulomatosis (LYG) is an angiocentric destructive proliferation of lymphoid cells predominantly involving the lungs, skin, kidneys, and central nervous system.
- It is divided into three grades, depending on the degree of necrosis and cellular atypia. The grades of