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coagulase/吐き気

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Management of serious staphylococcal infections in the outpatient setting.

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Patients with serious staphylococcal infections, e.g. endocarditis and osteomyelitis, need prompt and prolonged parenteral antibiotic treatment to ensure eradication of the causative pathogen. The major cost in the treatment of these infections is the long period of hospitalisation required for the

Cefepime as treatment for osteomyelitis and other severe bacterial infections.

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Cefepime, a novel, injectable alpha-methoxyimino aminothiazolyl cephalosporin, is active in vitro against many of the Gram-positive and Gram-negative bacteria which cause severe infections, including Pseudomonas aeruginosa. It is more active than existing third-generation cephalosporins against

Successful administration of quinupristin/dalfopristin in the outpatient setting.

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Intravenous administration of quinupristin/dalfopristin outside the hospital setting has not been reported previously. We describe 37 outpatients receiving quinupristin/dalfopristin iv for infections including osteomyelitis, bacteraemia, abscesses and cellulitis. The most frequent aetiological

A randomized trial of high-dose ciprofloxacin versus azlocillin and netilmicin in the empirical therapy of febrile neutropenic patients.

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A prospective, randomized trial comparing monotherapy with high-dose ciprofloxacin versus a standard combination regimen of azlocillin and netilmicin in the empirical treatment of febrile episodes in neutropenic patients was performed. One hundred and forty-six patient episodes were randomized, but

New developments in the management of severe skin and deep skin structure infections - focus on tedizolid.

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Tedizolid, a novel oxazolidinone, is approved for treatment of acute bacterial skin and skin structure infections (ABSSSIs). Tedizolid offers several potential advantages over current ABSSSI treatment options. First, tedizolid has a prolonged half-life, which allows for once-daily dosing. Second,

Food Poisoning Outbreak in a Military Establishment.

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BACKGROUND An outbreak of food poisoning involving 121 persons of a military establishment was investigated. METHODS On investigation, a total of 94 persons became ill, with an attack rate of 77.7%. The symptoms included nausea, vomiting, abdominal pain, diarrhoea, weakness and fever. The mean

High dose intravenous ciprofloxacin in febrile neutropenic patients.

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We have evaluated the use of high-dose intravenous ciprofloxacin as monotherapy in the empirical therapy of febrile episodes in neutropenic patients during the course of a randomized trial comparing ciprofloxacin with a standard combination regimen. Sixty-four episodes of fever were studied in a

[Chemotherapy with imipenem/cilastatin for severe infections accompanied by malignant hematological disorders].

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The clinical and bacteriological efficacy of imipenem/cilastatin (IPM/CS) was evaluated in 30 cases of serious infections associated with hematological malignancies. 1. Among 28 evaluable cases, excellent efficacy was obtained in 6 cases and good effectiveness in 10 cases, resulting in a high

[A case of toxic shock syndrome secondary to mastitis caused by methicillin-resistant Staphylococcus aureus].

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Toxic Shock Syndrome (TSS) secondary to mastitis is seldom described. We present a case of TSS due to postpartum mastitis caused by Methicillin-resistant Staphylococcus aureus (MRSA). Five weeks after giving birth to a healthy boy, a 23-year-old secundipara was readmitted to the hospital with a

Bacterial pituitary abscess: an unusual cause of panhypopituitarism.

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OBJECTIVE To describe a case of primary bacterial pituitary abscess manifesting as hypopituitarism. METHODS We present the case history, hormonal and bacteriologic data, and findings on imaging studies in a 34-year-old man. RESULTS The patient had an 8-month history of intermittent fever, headache,

Prolonged triple therapy for persistent multidrug-resistant Acinetobacter baumannii ventriculitis.

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OBJECTIVE A case of persistent multidrug-resistant (MDR) Acinetobacter baumannii ventriculitis successfully treated with a prolonged and novel combination of antimicrobials is reported. CONCLUSIONS A 38-year-old, 84-kg Caucasian woman with a recent history of craniotomy was admitted with nausea,

[Evaluation of the epidemiological, clinical and laboratory findings in continuous ambulatory peritoneal dialysis related peritonitis attacks].

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The aims of this study were to assess epidemiological features, clinical outcomes, laboratory findings, causative organisms and treatment approach for continuous ambulatory peritoneal dialysis (CAPD) -related peritonitis cases. A total of 50 patients (35 male, 15 female; age range: 18-83 years, mean

[New treatment option for gram-positive infections in critically ill patients - overview over linezolid].

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BACKGROUND During the last decade, there has been an emergence of multiresistant Gram-positive bacteria in intensive care units. Oxazolidinones are a new class of antibiotics without cross-resistance to other antimicrobial agents, and linezolid was recently introduced as first oxazolidinone on the

[Effectiveness and tolerance of cefixime in the treatment of acute pyelonephritis].

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In a prospective, open clinical study, 50 urological patients with acute pyelonephritis were treated with the oral cephalosporin cefixime. The medication (2 x 200 mg/day) was given for seven to ten days. Clinical, bacteriological as well as hematological examinations were carried out prior to,

Comparison of three-day temafloxacin with seven-day ciprofloxacin treatment of urinary tract infections in women.

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BACKGROUND Temafloxacin is a new broad-spectrum arylfluoroquinolone antimicrobial with an extended serum half-life. METHODS In this large, multicenter, double-blind clinical trial, 404 women with acute, uncomplicated urinary tract infections (UTI) were randomized to receive temafloxacin 400 mg once
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