gamma linolenic acid/sarcoma

In this study it is shown that gamma-linolenic acid (GLA) at concentrations of 10, 20 and 50 micrograms/ml has a dose-responsive inhibitory effect on mitosis in osteogenic sarcoma cells after exposure for 24, 48 and 72 hours, respectively. GLA also has marked effects on the morphology of the nucleus

Gamma-linolenic acid has been shown to suppress the rate of proliferation of a number of malignant cell lines in culture. To test the proposal that this was a specific prostaglandin 1- or 2-series effect, 379 batches of MG63 human osteogenic sarcoma cells were seeded in Greiner flasks and cultured

A statistically highly significant growth-suppressive effect of the prostaglandin precursor gamma-linolenic acid (GLA) on MG63 human osteogenic sarcoma and oesophageal carcinoma cells in culture was found. In view of the results reported on the growth-suppressive effect of GLA on cancer cells in

The effects of gamma-linolenic acid (GLA) on growth of cells of the continuous murine sarcoma line M52B were investigated in vitro. Prostaglandin (PG) production by these cells after GLA treatment was also measured. GLA inhibited the growth of M52B cells and became overtly toxic at high doses or

Acquired immunodeficiency syndrome (AIDS) is caused by human immunodeficiency virus (HIV) that is characterized by profound immunodeficiency, opportunistic infections and Kaposi's sarcoma. As yet no effective therapy is available for AIDS, though retroviral drugs are able to prolong life and contain

Earlier studies performed both by us and by others have demonstrated that some n-3 and n-6 fatty acids can inhibit the growth of tumour cells in vitro. Though studies done with various types of oils rich in n-3 and n-6 fatty acids did show that the tumour incidence and growth can be modified, there