Development of one ore more of the following gastrointestinal complications:
necrotizing enterocolitis (stage ≥2)
spontaneous intestinal perforation
feeding intolerance, defined as enteral feeding withholding ≥1 day because of suggestive clinical signs

no evidence of gastrointestinal complications during the hospitalization

Placental Insufficiency

NEC - Necrotizing Enterocolitis

Newborn, Premature

Feeding Disorder Neonatal

Neonatal Intensive Care Unit of the S.Orsola-Malpighi Hospital

Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.

Splanchnic Oxygenation and Perfusion Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler: Pattern Assessment and Correlation With Feeding Intolerance

Increase/reduction of SrSO2 values in response to enteral feeds in infants who have developed gastrointestinal complications during their hospitalization.

Luigi Corvaglia

Associate Professor, University of Bologna (Italy)

Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi

Study arm was fed with probiotics as infloran 125mg/kg/dose twice daily by adding it to breast milk or mixed feeding (breast and formula) for 6 weeks; the control arm was fed with breast milk or mixed feeding without probiotics.

Enterocolitis, Necrotizing

Study group was fed with probiotics as infloran 125mg/kg/dose twice daily by adding it to breast milk or mixed feeding (breast and formula) for 6 weeks;

infloran

Study group was fed with infloran [Lactobacilli acidophilus (CFU 109 NCDO 1748, obtained from the National Collection of Dairy Organisms)] and Bifidobacteria bifidum [(CFU 109, NCDO 1453 obtained from the National Collection of Dairy Organisms)]; Laboratorio Farmaceutico S.I.T S.r.I ITALY] 125mg/kg/dose twice daily by adding it to breast milk or mixed feeding (breast and formula) for 6 weeks;

Department of Pediatrics, Children Hospital, China Medical University, Taichung, Taiwan

Probiotics Reduce Incidence of Necrotizing Enterocolitis for Very Low Birth Weight Infants

Phase 2 Study of Oral Probiotics Reduce the Incidence and Severity of Necrotizing Enterocolitis for Very Low Birth Weight Infants -Multi-Center Randomized Control Trial

gastroschisis/hypoxia

Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.

Probiotics Reduce Incidence of Necrotizing Enterocolitis for Very Low Birth Weight Infants

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