The present invention is directed to methods for the prophylactic and therapeutic treatment of retinal ischemia and retinal inflammation. The methods involve the administration of an inhibitor of the protein tyrosine kinase pathway to an animal, such as a mammal, in particular a human, in an amount sufficient to treat the retina for ischemia or inflammation prophylactically or therapeutically. The inhibitor of the protein tyrosine kinase pathway is preferably genistein or an analogue or prodrug thereof or a pharmaceutically acceptable salt of any of the foregoing.

Johns Hopkins University, School of Medicine

Use of a protein tyrosine kinase pathway inhibitor in the treatment of retinal ischmemia or ocular inflammation

Compositions containing a combination of hydroxytyrosol and resveratrol or liqustilide or (-)-epigallocatechin gallate or honokiol or genistein or Magnolia bark extract or a combination of oleuropein and resveratrol or ligustilide are used to treat inflammatory disorders.

genistein/inflammation

Use of a protein tyrosine kinase pathway inhibitor in the treatment of retinal ischmemia or ocular inflammation

Compositions

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