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gliadin/dental caries

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11 結果

Folding interpenetration in a gliadin model: the role of the characteristic octapeptide motif.

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A model of a rheologically relevant protein, omega-gliadin, is proposed and studied in this work by means of molecular dynamics techniques. The model is based on an octapeptide repeat motif that is experimentally described as characteristic of that protein and as constituting it almost entirely. The
In order to find a connection between the alteration of oral tissues and genetic predisposition to inflammatory and destructive processes in oral media, the cytokine profile of the oral fluid of clinically healthy individuals was determined for various blood group affiliations according to the AB0

Improved Bioavailability of Curcumin in Gliadin-Protected Gold Quantum Cluster for Targeted Delivery.

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This study deals with the synthesis of a gliadin-stabilized gold quantum cluster (AuQC) for the encapsulation of curcumin (CUR) and its targeted delivery to the cancer cell. CUR is an anticancer drug containing a hydrophobic polyphenol derived from the rhizome of Curcuma longa. The

Effect of Rothia mucilaginosa enzymes on gliadin (gluten) structure, deamidation, and immunogenic epitopes relevant to celiac disease.

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Rothia mucilaginosa, a natural microbial inhabitant of the oral cavity, cleaves gluten (gliadin) proteins at regions that are resistant to degradation by mammalian enzymes. The aim of this study was to investigate to what extent the R. mucilaginosa cell-associated enzymes abolish gliadin immunogenic

Discovery of a novel and rich source of gluten-degrading microbial enzymes in the oral cavity.

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BACKGROUND Celiac disease is a T cell mediated-inflammatory enteropathy caused by the ingestion of gluten in genetically predisposed individuals carrying HLA-DQ2 or HLA-DQ8. The immunogenic gliadin epitopes, containing multiple glutamine and proline residues, are largely resistant to degradation by

Population distribution of human salivary amylases: differential inhibition by wheat protein.

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Based upon response to an inhibitor from wheat gliadin, 80 random samples of human salivary amylase were separated into three phenotypic groups. Each phenotype occurred with a high frequency rendering this a polymorphinc locus. The susceptibility to the inhibitor may be a useful marker for studies

[Infant nutrition in Switzerland 1978. A prospective study on feeding habits during the first 6 months. II. Artificial feeding].

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The term "artificial feeding" includes a) the various infant formulas (including homemade formulas) substituting or supplementing mother's milk; b) the so-called "Beikost", i.e. minor additions to mothers milk or formula, such as fruit juices, fruit, meat and eggs; c) solid foods replacing part of

Clinical importance of celiac disease in patients with recurrent aphthous stomatitis.

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OBJECTIVE Recurrent aphthous stomatitis is a common disease of the oral mucosa that is characterized by recurrent, painful ulcers of unknown etiology. The association between celiac disease and recurrent aphthous stomatitis has been evaluated in several studies, but variable results have been

Clinical utility of serologic testing for celiac disease in ontario: an evidence-based analysis.

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OBJECTIVE OF ANALYSIS: The objective of this evidence-based evaluation is to assess the accuracy of serologic tests in the diagnosis of celiac disease in subjects with symptoms consistent with this disease. Furthermore the impact of these tests in the diagnostic pathway of the disease and decision

Salivary Gluten Degradation and Oral Microbial Profiles in Healthy Individuals and Celiac Disease Patients.

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Celiac disease (CD) is a chronic immune-mediated enteropathy induced by dietary gluten in genetically predisposed individuals. Saliva harbors the second highest bacterial load of the gastrointestinal (GI) tract after the colon. We hypothesized that enzymes produced by oral bacteria may be involved

Changes in jejunal mucosa after long-term feeding of germfree rats with gluten.

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BACKGROUND Coeliac disease (CD) or gluten-sensitive enteropathy is a chronic gastrointestinal disease of children and adults. An experimental model using inbred germfree rats has been developed to study the effects of intragastric gliadin application on intestinal mucosa. METHODS AVN strain Wistar
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