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hyperuricemia/obesity

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11 結果

Pinitol and derivatives thereof for the treatment of metabolic disorders

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SUMMARY OF THE INVENTION The invention relates to pinitol and derivatives and metabolites thereof and compositions containing same for treating conditions associated with insulin resistance. These include disorders such as diabetes mellitus and its chronic complications; obesity; hyperlipidemias and

Pinitol and derivatives thereof for the treatment of metabolic disorders

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SUMMARY OF THE INVENTION The invention relates to pinitol and derivatives and metabolites thereof and compositions containing same for lowering plasma free fatty acids levels and for treating conditions associated with insulin resistance. These conditions associated with insulin resistance can

Modulators of PPAR and methods of their preparation

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BACKGROUND OF THE INVENTION Peroxisome Proliferator-Activated Receptors (PPARs) are implicated in a number of biological processes and disease states including Type 2 diabetes, hyperinsulinemia, hyperlipidemia, hyperuricemia, hypercholesteremia, atherosclerosis, one or more risk factors for

Pyrazolopyridine compound and processes for preparation thereof

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The present invention relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof. More particularly, it relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof, which are adenosine antagonists and possess various pharmaceutical actions

Substituted triazoles as modulators of PPAR and methods of their preparation

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STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT NOT APPLICABLE REFERENCE TO A "SEQUENCE LISTING," A TABLE, OR A COMPUTER PROGRAM LISTING APPENDIX SUBMITTED ON A COMPACT DISK NOT APPLICABLE BACKGROUND OF THE INVENTION Peroxisome Proliferator-Activated

Ketohexokinase (KHK) iRNA compositions and methods of use thereof

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted electronically in ASCII format and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Jul. 28, 2016, is named Seq_Listing_121301_01202.txt and is 116,250 bytes in

Compositions and methods for the treatment of metabolic syndrome

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PRIORITY The present application claims the benefit of Indian Provisional Patent Application No. 1853/CHE/2012 filed on 10 May 2012 and the International Application No. PCT/IB2013/051596 filed on 28 Feb. 2013, the entire disclosure of which is relied on for all purposes and is incorporated into

Compositions and methods for the treatment of metabolic syndrome

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PRIORITY This application is a national phase filing of the Patent Cooperation Treaty (PCT) application # PCT/IB2013/050904 titled COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC SYNDROME filed on Feb. 3, 2013 Published with WIPO Publication # WO/2013/167996, which further claims priority to

Compositions and methods for the treatment of metabolic syndrome

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PRIORITY The present application claims the benefit of Indian Provisional Patent Application No. 1836/CHE/2012 filed on 10 May 2012 and the International Application No. PCT/IB2013/050907 filed on 3 Feb. 2013; the entire disclosure of which is relied on for all purposes and is incorporated into this

SGLT-2 inhibitors, methods of making them, and uses thereof

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FIELD OF THE INVENTION The present invention relates to compounds which are inhibitors of sodium dependent glucose co-transporter-2 (SGLT-2), methods of making them, and uses thereof. BACKGROUND OF THE INVENTION According to the World Health Organization (WHO), in 2009, more than 220 million people

Pyrazolopyridine compounds which have useful pharmaceutical utility

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The present invention relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof. More particularly, it relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof, which are adenosine antagonists and posses various pharmaceutical actions
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