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ischemia/obesity

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Polycosanols from Ericerus pela wax

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FIELD OF THE INVENTION The present invention relates generally to a method for the generation of a composition of matter comprised of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from a novel natural source--a wax secreted by the Chinese wax soft scale insect,

Polycosanols from Ericerus pela wax

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FIELD OF THE INVENTION The present invention relates generally to a method for the generation of a composition of matter comprised of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from a novel natural source--a wax secreted by the Chinese wax soft scale insect,

Polycosanols from Ericerus pela wax

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FIELD OF THE INVENTION The present invention relates generally to a method for the generation of a composition of matter comprised of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from a novel natural source--a wax secreted by the Chinese wax soft scale insect,

Polycosanols from ericerus pela wax

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FIELD OF THE INVENTION The present invention relates generally to a method for the generation of a composition of matter comprised of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from a novel natural source--a wax secreted by the Chinese wax soft scale insect,

Cardioprotective phosphonates and malonates

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FIELD OF THE INVENTION This invention relates to pyridoxine phosphonate analogues, to pyridoxine malonate analogues, to their preparation, to pharmaceutical compositions thereof, and to treatments for cardiovascular and related diseases, for example, hypertrophy, hypertension, congestive heart

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Piperidine derivative compounds and drugs containing the compounds as the active ingredient

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TECHNICAL FIELD The present invention relates to a piperidine derivative. More specifically, the present invention relates to (1) a piperidine derivative of formula (I) ##STR00002## (2) a method for the preparation thereof, (3) a composition comprising it as an active ingredient, (4) a compound of

2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors

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BACKGROUND OF THE INVENTION Approximately 100 million people worldwide suffer from type II diabetes, which is typically characterized by hyperglycemia due to excessive hepatic glucose production and peripheral insulin resistance, the root causes for which are as yet unknown. Hyperglycemia is

2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors

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BACKGROUND OF THE INVENTION Approximately 100 million people worldwide suffer from type II diabetes, which is typically characterized by hyperglycemia due to excessive hepatic glucose production and peripheral insulin resistance, the root causes for which are as yet unknown. Hyperglycemia is

2-Amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors

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BACKGROUND OF THE INVENTION Approximately 100 million people worldwide suffer from type II diabetes, which is typically characterized by hyperglycemia due to excessive hepatic glucose production and peripheral insulin resistance, the root causes for which are as yet unknown. Hyperglycemia is

2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors

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BACKGROUND OF THE INVENTION Approximately 100 million people worldwide suffer from type II diabetes, which is typically characterized by hyperglycemia due to excessive hepatic glucose production and peripheral insulin resistance, the root causes for which are as yet unknown. Hyperglycemia is

Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids

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FIELD OF THE INVENTION The present invention concerns the preparation and uses of adamantanamines (e.g. memantine, amantadine and rimantadine) and neramexane(s) salts of thiomolybdic acids and thiotungstic acids. Their pharmaceutical compositions incorporate two complementary, bioavailable

Bicyclic inhibitors of glycogen synthase kinase 3

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FIELD OF THE INVENTION This invention relates to new bicyclic compounds that inhibit the activity of glycogen synthase kinase 3 (GSK3), to pharmaceutical compositions containing the compounds and to the use of the compounds and compositions, alone or in combination with other pharmaceutically active
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