herbal medication which has antioxidant, anti-inflammatory and anticarcinogenesis effect.

topical triamcinolone acetonide is the gold standard treatment of oral lichen planus.

Oral Lichen Planus

herbal medication which has antioxidant, anti-inflammatory and anticarcinogenesis effect

topical chamomile

Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planus

Pain measure using Numerical rating scale

Reduction in clinical sign score using Thongprasom et al

Esraa Nashat

11 saraya st - manial - cairo

Cairo University

The supervisor(AA) will be blind. The principle investigator(EN) will supply the patient with the treatment.
The supervisor (AA) will assess the clinical parameters before treatment , between visits and at the end of the treatment.
Statistician will be blind. Double - blind study.

The infusion of chamomile will be prepared in the clinic with 400 mL of distilled water and 10 g of chamomile flowers (Chamomile classic infusion, Royal Herbs).
Ice cubes will be prepared in special ice trays placed in the chemotherapy center for this purpose.
Patient will receive a cup of ice cubes which is continuously replenished before being emptied.
Patients will be instructed to swish the ice cubes around their oral cavities starting 5 minutes before chemotherapy infusion, continuing 30 minutes throughout the session and for additional 35 minutes after completion of intravenous chemotherapy session.

The plain icecubes will be prepared in the clinic with 400 mL of distilled water.
Ice cubes will be prepared in special ice trays placed in the chemotherapy center for this purpose.
Patient will receive a cup of ice cubes which is continuously replenished before being emptied.
Patients will be instructed to swish the ice cubes around their oral cavities starting 5 minutes before chemotherapy infusion, continuing 30 minutes throughout the session and for additional 35 minutes after completion of intravenous chemotherapy session.

Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy

The infusion of chamomile will be prepared in the clinic with 400 mL of distilled water and 10 g of chamomile flowers (Chamomile classic infusion, Royal Herbs). Patients are asked to swish the chamomile ice cubes around their oral cavities starting 5 minutes before chemotherapy infusion, continuing 30 minutes throughout the session and for additional 35 minutes after completion of intravenous chemotherapy session.

Chamomile oral cryotherapy

The plain icecubes will be prepared in the clinic with 400 mL of distilled water. Patients are asked to swish the ice cubes around their oral cavities starting 5 minutes before chemotherapy infusion, continuing 30 minutes throughout the session and for additional 35 minutes after completion of intravenous chemotherapy session.

Oral cryotherapy

National Cancer Institute

Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy.

Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy: (A Randomized Pilot Study)

Primary outcome is measured using Children International Mucostitis Evaluation Scale (CHIMES).ChIMES1-4 each received a score of 0-5 where 5 is the worst degree of symptoms. ChIMES5 and ChIMES6 received a score of 1 or 0 if the child had received pain medications or not. Finally, ChIMES7 received a score of 1or 0 if oral ulcers were present or not. Any question that was scored as missing or 'I can't tell' was excluded from the total possible score. If all the questions were answered, the maximum score was 23. The ChIMES Total Score was the sum of all scores; 'I can't tell' responses and missing responses both received a score of 0. The ChIMES Percentage Score was the ChIMES Total Score over the total maximum score taking into account 'I can't tell' responses (by subtracting these items from the maximum score) multiplied by 100. Higher values indicate a worse outcome.

Assessed using Oral Mucositis World Health Organization Toxicity Scale.It represents grades of oral mucositis ranging from 0-4 with higher grades indicating worse outcome.

Dina Yousef Abdel Aleem Essa

Master Degree Student

National Cancer Institute, Egypt

The Chamomile recutita mouthwash 1% was administered two times daily for 30 days.

The Chamomile recutita mouthwash 2% was administered two times daily for 30 days.

The standard protocol at the unit, which comprises mouthwash with chlorhexidine 0,12%; oral hygiene teaching. In case the toothbrush cannot be used due to gingival or oral mucosa bleeding, gauze is used to replace it.

The Chamomile recutita mouthwash 0.5% was administered two times daily for 30 days, starting on the first day of chemotherapy.

Mucositis

The Chamomile recutita mouthwash was administered two times daily for 30 days. 10 mL of this solution was swished around in the mouth for approximately one minute and then expectorated.

mouthwash with Chamomilla

The standard protocol at the unit, which comprises mouthwash with chlorhexidine 0,12% twice a day; oral hygiene teaching, recommended at least three times per day and always after meals. For brushing, brushes with extra-soft bristles and non-abrasive toothpaste are used. In case the toothbrush cannot be used due to gingival or oral mucosa bleeding, gauze is used to replace it.

matricaria chamomilla/抗炎症薬

Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planus

Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy.

Use of Chamomilla Recutita in Mucositis

4-Methylumbelliferone as a Treatment for Chronic HBV/HCV

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