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neoplasm metastasis/癲癇性発作

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[Seizure-induced brain injury in brain development and Zn2+ metastasis in hippocampus].

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Zn2 + is a novel ionic mediator of neurotoxic injury in central nervous system. Zn2 + homeostasis in hippocampal Zinc-rich mossy fiber (MF) pathway is important in keeping the balance between excitatory and inhibitory system, and in maintaining cognitive functions of the brain. Abnormal Zn2+

Seizures Prior to Whole-brain Irradiation for Metastatic Disease: Prevalence, Risk Factors and Association With Survival

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Background/aim: Seizures are a serious condition for patients with brain metastases. Prevalence, risk factors and a potential association of seizures with survival prior to whole-brain irradiation (WBI) for cerebral metastases were retrospectively

Risk of seizure and its clinical implication in the patients with cerebral metastasis from lung cancer.

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BACKGROUND The prevalence, risk factors, and clinical implication of seizure development were investigated in patients with metastatic brain tumors. METHODS Medical records and radiological findings were analyzed retrospectively in 258 patients with brain metastasis from lung cancer who underwent

Unexpected seizure attack in a patient with spinal metastasis diagnosed as posterior reversible encephalopathy syndrome.

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Seizure is a foreseeable risk in patients with brain lesion. However, seizure during treating non-brain lesion is not a familiar situation to neurosurgeon. Posterior reversible encephalopathy syndrome (PRES) is a relatively common situation after systemic chemotherapy. The aim of this study is to

Cerebral edema, altered mental status, seizures, acute stroke, leptomeningeal metastases, and paraneoplastic syndrome.

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Neurologic symptoms commonly occur in oncology patients, and in some cases they may be the presenting symptom of malignancy. Cancer-related neurologic syndromes are rarely pathognomonic and must be differentiated from other benign or serious conditions. This article reviews common neuro-oncologic

Cerebral edema, altered mental status, seizures, acute stroke, leptomeningeal metastases, and paraneoplastic syndrome.

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Neurologic symptoms commonly occur in oncology patients, and in some cases they may be the presenting symptom of malignancy. Cancer-related neurologic syndromes are rarely pathognomonic and must be differentiated from other benign or serious conditions. This article reviews common neuro-oncologic

The risk of developing seizures before and after surgery for brain metastases.

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Several risk factors have been shown to be associated with pre- and postoperative seizures in patients undergoing neurosurgical intervention for meningiomas and other primary brain tumors. This study aimed to identify risk factors associated with pre- and postoperative seizures in

Pre-Treatment Seizures in Patients With 1-3 Cerebral Metastases Receiving Local Therapies Plus Whole-brain Radiotherapy

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Background/aim: Seizures impair patients' quality of life. The prognostic role of pre-treatment seizures in patients with 1-3 cerebral metastases receiving local therapies plus whole-brain radiotherapy (WBRT) was investigated.
Background/aim: Seizures represent a major problem for patients with brain metastases. This study evaluated the role of seizures in patients receiving single-fraction radiosurgery (SRS) or multi-fraction stereotactic radiotherapy (FSRT).

Biomarkers of Seizure Activity in Patients With Intracranial Metastases and Gliomas: A Wide Range Study of Correlated Regions of Interest

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Introduction: Studies quantifying cortical metrics in brain tumor patients who present with seizures are limited. The current investigation assesses morphometric/volumetric differences across a wide range of anatomical regions, including temporal and extra-temporal, in patients with gliomas

Midline shift, seizures and acute neurological deterioration due to cranial vault metastases from prostatic carcinoma.

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Intracranial metastases from prostatic cancer are rare, but cranial vault metastases are not. Most patients who have vault metastases present with local symptoms such as pain. We describe a patient who presented with acute neurological symptoms as well as a midline shift, seizures and secondary

Diazepam prophylaxis of contrast media-induced seizures during computed tomography of patients with brain metastases.

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The effect of 5 mg of intravenous diazepam (Valium) on contrast media-associated seizure incidence was studied in a randomized controlled trial involving 284 patients with known or suspected brain metastases undergoing cerebral computed tomography. Of these patients, 188 were found to have brain

Incidence of seizure in adult patients with intracranial metastatic disease.

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Seizures have considerable impact on a patient's quality of life. While guidelines have been articulated to direct clinicians in their management of patients with IMD who suffer from seizure, there have been few attempts to identify the seizure rate in IMD and to determine which primary cancers may

Small cell lung cancer metastasis in the pituitary gland presenting with seizures and headache.

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We report an adult female with a small cell lung cancer (SCLC) pituitary metastasis who presented with seizures and headache. While headache is a common presentation of pituitary metastases, seizures have been very rarely reported. The patient was found on MRI to have a suprasellar tumor with

Seizure prophylaxis and melanoma brain metastases.

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Melanoma has a high propensity to metastasize to the brain. In patients with brain metastases (BM) survival is limited, neurologic morbidity is high, with seizure incidence reported up to 67%. Current guidelines recommend against antiepileptic drug prophylaxis (AED PPX) in patients without a history
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