neutropenia/hypoxia

Subjects and Methods: Study design and study setting The current study is a randomized, double-blinded placebo-controlled trial (RCT) that was conducted in Cairo University Abou ElReesh Children hospital, which is a university-affiliated teaching hospital in Egypt, to evaluate the effect of vitamin

In preclinical studies Pevonedistat has shown significant single agent activity against mouse xenograft models of AML cell Line HL-60. Also this effect seemed to be synergistically enhanced by combining it with Azacitidine. In clinical arena, Pevonedistat has shown single agent activity in heavily

Breast cancer is the most common non cutaneous cancer in U.S. women, with an estimated 63,960 cases of in situ disease and 266,120 cases of invasive disease in 2018. (American Cancer Society: Cancer Facts and Figures 2018). On the basis of ER, PR, and HER2/neu results, breast cancer is classified as

STUDY DESIGN 5.1 Study Description This open-label, non-randomized phase I trial is designed to assess the safety, tolerability and maximum tolerated dose (MTD)/recommended phase II dose (RPTD) of TH-302 plus pazopanib in adult subjects with advanced solid tumors. Patients will be accrued (enrolled)

Introduction: A concentrate for bicarbonate haemodialysis acidified with citric instead of the less physiologic acetic acid has been successfully implemented in the United States in the past 7 years [1-3]. Contrarily to traditional regional citrate anticoagulation, the small amount of citrate used