nicotine/悪性腫瘍

FIELD OF THE INVENTION The invention relates to methods of identifying a candidate compound which may inhibit estrogen receptor-dependent transcription or .alpha.9-nAChR overexpression and proliferation of nicotine-derived-compound-induced breast cancer cells. Particularly, an activating protein 1

FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,

FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,

FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,

FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,

FIELD OF THE INVENTION The present invention relates to transdermal devices and methods for controllable dispensing of a nutraceutical or an active substance such as a chemical substance, a medication, a drug, a stimulant or the like, to a human or other mammal for purposes of promoting longevity,

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates generally oncology and cancer susceptibility. More particularly, it concerns methods for assessing cancer susceptibility, particularly lung cancer susceptibility, to carcinogens in tobacco smoke and products. 2.

FIELD The present invention relates to methods and compositions useful for cancer diagnosis, prognosis, treatment and prevention. BACKGROUND Cancer causes a significant burden of disease around the world. In the United States, one of every three adults are expected to develop some form of cancer in

FIELD OF THE INVENTION This invention provides pharmaceutical compositions and compounds useful in methods of inhibiting cytochrome P450 2A6 and/or 2A13, reducing the use of tobacco products, reducing the exposure to nicotine and the harmful by-products associated with the use of tobacco products,

FIELD OF THE INVENTION The invention relates to small interfering RNAs (siRNAs) for inhibiting expression of .alpha.9-nAChR so as to inhibit breast cancer, methods to prevent/inhibit/treat malignant progression of nicotine-derived-compound-induced breast cancer (breast cancer induced by nicotine

BACKGROUND OF THE INVENTION Retinoids are a class of naturally occurring and synthetic derivatives of Vitamin A which function in vivo as regulators of a number of physiological functions including cellular proliferation, cytodifferentiation and embryonal morphogenesis. This class includes a number

BACKGROUND In other studies which we have made, we have considered the effects of glucosinolates. Glucosinolates are naturally-occurring constituents of cruciferous vegetables (Tookey, H. L., VanEtten, C. H. and Daxenbichler, M. E. (1980) Glucosinolates. In liener, I. E. (ed.), Toxic Constituents of

BACKGROUND In other studies which we have made, we have considered the effects of glucosinolates. Glucosinolates are naturally-occurring constituents of cruciferous vegetables (Tookey, H. L., VanEtten, C. H. and Daxenbichler, M. E. (1980) Glucosinolates. In Liener, I. E. (ed.), Toxic Constituents of

FIELD OF THE INVENTION The present invention relates to a chewing gum composition for eliminating nicotine, and more particularly to such a composition capable of eliminating the nicotine component from the body of a person chewing the chewing gum. DESCRIPTION OF THE PRIOR ART Nicotine is known as a

Several patents attempt to medicate cigarettes generally (U.S. Pat. No. 977,635 by A. B. Klein; U.S. Pat. No. 1,974,242 by J. L. Jordan, Jr. et al.; U.S. Pat. No. 2,418,296 by S. S. Frederickson; U.S. Pat. No. 4,021,364 by P. Speiser et al.) with vitamins (U.S. Pat. No. 2,198,188 by A. Viscardi;