noradrenaline/脳卒中

Depression is common after stroke. While several reports have been published on the use of antidepressants such as selective serotonin reuptake inhibitors and tricyclics for the treatment of post-stroke depression (PSD), no previous study has examined the use of a selective serotonin and

Adrenergic innervation in the main trunk of the mesenteric artery was studied in stroke-prone spontaneously hypertensive rats (SHRSP) as well as in a new strain of SHRSP (M-SHRSP) and was compared with that of normotensive Wistar Kyoto rats (WKY). Noradrenaline (NA) content and high K-induced NA

1. Stroke-prone spontaneously hypertensive rats (SHRSP) are a strain of rat that exhibit severely high blood pressure and stroke attacks at an early age, but their heart function in vitro has seldom been studied in detail. Although the activity of the sympathetic nervous system is known to increase

Influences of endothelium on contractions of aortic ring preparations from 15 to 17 weeks old stroke-prone spontaneously hypertensive rats (SHRSP) and age-matched Wistar-Kyoto rats (WKY) were compared. Noradrenaline-induced contraction was potentiated by endothelium removal; the potentiation was

The concentration of noradrenaline was measured in various regions of the brain and spinal cord of spontaneously hypertensive rats, stroke-prone spontaneously hypertensive rats and normotensive Wistar/Kyoto controls. Elevated noradrenaline levels were consistently found in the pons, cerebellum and

1. Partial replacement of sodium by potassium in the diet attenuates the rise in blood pressure in stroke-prone spontaneously hypertensive rats (SHR-SP). 2. The blood pressure-lowering effect of potassium cannot be ascribed to a reduction in intravascular volume. 3. The increased dietary intake of

OBJECTIVE Both animal and human data suggest that noradrenergic stimulation may enhance motor performance after brain damage. We conducted a placebo-controlled, double-blind and crossover design study to investigate the effects of noradrenergic stimulation on the cortical motor system in hemiparetic

OBJECTIVE To explore the relation between plasma neurotransmitters (Glutamic acid, GAA; γ-aminobutyric acid, GABA; 5-hydroxytryptamine, 5-HT; and noradrenaline, NE) and depression in acute hemorrhagic stroke. METHODS Objectives were screened from consecutive hospitalized patients with acute stroke.

Depression occurs frequently in post-stroke patients and appears to be associated with an impairment in their rehabilitation and functional recovery. Although selective serotonin reuptake inhibitors (SSRI) are often used in post-stroke depression (PSD), it has been observed that only a subset of

OBJECTIVE Depression is a significant complication of stroke. The effectiveness of antidepressant drugs in the management of post-stroke depression (PSD) has been widely investigated. However, the choice of antidepressant drug is critically influenced by its safety and tolerability and by its effect

Post-stroke depression (PSD) is an important complication of stroke, leading to increased disability and mortality. Given that there is no consensus on which treatment is optimal for PSD, we aimed to evaluate the relative efficacies of available pharmacological and non-pharmacological interventions.

The role of the sodium-calcium (Na-Ca) exchange in vascular smooth muscle contraction was examined in tail artery rings isolated from stroke-prone spontaneously hypertensive rats (SHRSP) and in normotensive Wistar-Kyoto rats (WKY). The rings were repeatedly stimulated with noradrenaline (1 microM)