pacific/癲癇性発作

OBJECTIVE To evaluate the efficacy, safety, and tolerability of perampanel, a selective, non-competitive, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, as an adjunctive treatment for patients with refractory partial-onset seizures (POS) from

Purpose of review: We present information on cannabis policy, demand, and supply in the Asia-Pacific region. Method: A systematic review of peer-reviewed articles using PubMed, MEDLINE, and reliable sources was conducted. We

A 21-yr-old intact male walrus ( Odobendus rosmarus divergens) presented with acute onset of shifting lameness, initially associated with breeding behaviors. Further clinical signs manifested, including muscle tremors, anorexia, hematuria, and coughing. Diagnostics were limited, as the animal would

Marine organisms have yielded a variety of metabolites with neuropharmacological applications. Here we describe the isolation and pharmacological characterization of four novel, neurologically active purines 1-4, isolated from Haplosclerida sponges collected in the Republic of Palau. The structures

OBJECTIVE To examine the relevance of ABCC2 polymorphisms to drug responsiveness in epilepsy cohorts from the Asia Pacific region. METHODS The rs2273697 and rs3740066 polymorphisms were genotyped in 2056 Malaysian (55%), Hong Kong (32%) and Japanese (13%) epilepsy patients. RESULTS Significant

Epidemiological studies are carried out by the National Drug Research Centre, Malaysia on various aspects of drug use and abuse. One of the groups of substances studied are the opioid agonist-antagonists. The study utilised information submitted to international agencies and obtained through a

BACKGROUND The provision of pediatric palliative care in Asia Pacific varies between countries and availability of essential medications for symptoms at the end of life in this region is unclear. OBJECTIVE To determine medications available and used in the management of six symptoms at the end of

Neonatal seizures occurred in 23 infants, a rate of 2.33 per 1000, 1978-81. In two infants these were due to congenital central nervous system malformation and in two infants hypocalcaemia. Hypoxic encephalopathy was the cause of the seizures in 19 infants, two of whom also suffered perinatal

Saipan is a United States (US) territory Western Pacific island where little recent data exists regarding epidemiology, clinical presentation, and standard of care for pediatric seizures. This paper characterizes these features in Saipan's pediatric population with comparisons to mainland US. This

BACKGROUND Takuto Rehabilitation Center for Children is located in Sendai, the capital of the Miyagi prefecture, and faces the Pacific Ocean. The tsunami caused by the Great East Japan Earthquake resulted in tremendous damage to this region. Many physically handicapped patients with epilepsy who are

The "alarm" substance of the top smelt, Atherinops affinis (Ayres), has been isolated by extraction with methanol or ether from suffocated top smelt. These concentrated extracts, when introduced into an aquarium containing top smelt, induce a strong alarm reaction in the fish, characterized by rapid

Extracorporeal cardiopulmonary resuscitation (ECPR) is an emerging therapy for refractory cardiac arrest. The purpose of this study was to analyze and report characteristics and outcomes of adult patients treated with ECPR after out-of-hospital cardiac arrest (OHCA) in a large international

OBJECTIVE We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis. METHODS A retrospective chart review was undertaken at two tertiary paediatric hospitals in Australia and New