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pyridine/breast neoplasms

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Modulators of the p70S6 kinase for use in the treatment of brain disorders and triple-negative breast cancer

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CROSS REFERENCE TO RELATED APPLICATIONS This application is a national stage filing under section 371 of International Application No. PCT/EP2016/053172, filed on Feb. 15, 2016, and published on Aug. 25, 2016 as WO 2016/131776, which claims priority to Great Britain Application No. 1502567.9, filed

Pyridine derivatives as rearranged during transfection (RET) kinase inhibitors

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This application is a 371 of International Application No. PCT/IB2014/059817, filed 14 Mar. 2014, which claims priority of PCT/CN2014/072449, filed 24 Feb. 2014; PCT/CN2013/090059, filed 20 Dec. 2013; and PCT/CN2013/072683, filed 15 Mar. 2013. FIELD OF INVENTION This invention relates to novel

Chemical compounds

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The present invention relates to certain pyridine or pyrimidine derivatives for use in the treatment of certain diseases in particular to proliferative disease such as cancer and in the preparation of medicaments for use in the treatment of proliferative disease, to novel pyridine or pyrimidine

Chemical compounds

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The present invention relates to certain pyridine or pyrimidine derivatives for use in the treatment of certain diseases in particular to proliferative disease such as cancer and in the preparation of medicaments for use in the treatment of proliferative disease, to novel pyridine or pyrimidine

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful

Histone demethylase inhibitors

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BACKGROUND A need exists in the art for an effective treatment of cancer and neoplastic disease. BRIEF SUMMARY OF THE INVENTION Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions
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