retinoblastoma/edema

A 30-month-old boy presented to a Haitian emergency department with proptosis, periorbital edema, and progressive blindness. Bedside ultrasound examination revealed bilateral ocular masses with dense calcifications pathognomonic for retinoblastoma. This case illustrates the diagnostic utility of

OBJECTIVE To evaluate the clinical features and management of diffuse infiltrating retinoblastoma. METHODS Retrospective case series. METHODS Thirty-four eyes in 32 patients. METHODS The patients' records were reviewed for patient and tumor features, ocular management, histopathologic findings, and

OBJECTIVE To determine intravitreal and plasma concentrations and retinal toxicity after transcorneal intravitreal injection of 1 μg and 2 μg of topotecan (Hycamtin). METHODS Twelve healthy albino rabbits were included in this in vivo experiment. Six anesthetized albino rabbits received a single

BACKGROUND Treatment of eyes with retinoblastoma failing systemic chemoreduction and external beam radiotherapy is seldom efficacious. This study compares the efficacy and toxicity of intra-arterial ophthalmic artery chemotherapy (IAO) to our historical cohort of sequential periocular and systemic

OBJECTIVE The purpose of this study was to investigate tumor control efficacy of paclitaxel in the treatment of retinal tumors harbored by the LH beta-Tag murine transgenic model of retinoblastoma. METHODS LH beta-Tag-positive mice (n = 5) 10 weeks of age received two 20-microL subconjunctival

OBJECTIVE To study the atypical presentations of retinoblastoma in our institution. METHODS Retrospective, clinical study. RESULTS A total of 392 cases of retinoblastoma were reviewed; 72.2% of the patients had leukocoria, 13% had proptosis, 10% had strabismus, 1.5% were asymptomatic (detected on

OBJECTIVE To investigate the safety of treatment with ophthalmic artery cannulation for intra-arterial chemotherapy (IAC) for children with intraocular retinoblastoma (RB). METHODS In the RB Treatment Center of General Hospital of Armed Police Forces between January 2009 and September 2011, 42

OBJECTIVE To identify the maximum tolerated dose and dose-limiting toxicity of periocular topotecan in patients with relapsed or resistant intraocular retinoblastoma who are facing imminent enucleation. METHODS For this phase I study, a starting dose of 0.5 mg of periocular topotecan administered

OBJECTIVE The purpose of this study is to report the complication profile and safety evaluation of supraselective intra-arterial melphalan chemotherapy in children undergoing treatment with advanced retinoblastoma. METHODS Twelve eyes of 10 children with advanced retinoblastoma (Reese-Ellsworth

OBJECTIVE To evaluate the safety and efficacy of posterior sub-Tenon's carboplatin injection compared to intravitreal melphalan injection in the management of retinoblastoma (RB) with secondary vitreous seeds. The outcome measures were vitreous seeds regression, need for other treatment modalities

OBJECTIVE To demonstrate the utility of hand-held spectral-domain optical coherence tomography (SD-OCT) in assessing retinal structure in cases of macular retinoblastoma. METHODS In this retrospective, observational case series, three young children with macular retinoblastoma were treated at a

OBJECTIVE To analyze the reasons of orbital exenteration for orbital retinoblastoma (RB) patients. METHODS Retrospective case series study. Clinical records were reviewed retrospectively of 17 orbital RB patients who had undergone exenteration from November 1999 to November 2010 at Armed Police

Central nervous system (CNS) involvement is not rare in extraocular retinoblastoma, and it is not surprising to find it in view of its route of spread. However, although spinal recurrence presenting as spinal cord compression (SCC) is a form of CNS involvement, it is extremely rare. This report