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senecio jacobaea/悪性腫瘍
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In-vitro antiproliferative effects on human tumour cell lines of extracts and jacaranone from Senecio leucanthemifolius Poiret.
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We have studied the cytotoxic activity of extracts and jacaranone from Senecio leucanthemifolius Poiret. Extracts from S. leucanthemifolius were able to inhibit the in-vitro proliferation of a series of human tumour cell lines. The dichloromethane extract demonstrated effective cytotoxic activity
Cytotoxicity and cell cycle analysis of Asparagus laricinus Burch. and Senecio asperulus DC. on breast and prostate cancer cell lines.
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Aims
Medicinal plants play an important role in our African communities for treatment and prevention of various diseases including cancer. This study was aimed on evaluating the cytotoxicity activities of Asparagus laricinus Burch. and Senecio asperulusThe selective cytotoxicity elicited by phytochemical extract from Senecio graveolens (Asteraceae) on breast cancer cells is enhanced by hypoxia.
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Breast cancer is the second cause of cancer‑related deaths in woman and the incidence of the disease has increased worldwide, in part due to improvements in early detection. Several drugs with anticancer effects have been extracted from plants in the last 20 years, many of which are particularly
Combined effect of cyclophosphamide and extracts of Crotalaria and Senecio plants on experimental tumours.
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The combined effect of cyclophosphamide (CTX) and extracts of six patients belonging to Crotalaria and Senecio genera was assessed on experimental transplantable S180 (both ascitic and solid forms) tumour. Successive petroleum ether and methanolic extracts from these plants were obtained. The
In vitro effects on proliferation, telomerase activity and apoptosis of an eremophilanoid sesquiterpene from Senecio oldhamianus maxim in cultured human tumor cell lines.
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8,11-Dioxol-6-en-9alpha, 10alpha-epoxy-8beta-hydroxyeremophilane (HEM), a new eremophilanoid sesquiterpene, was isolated from Senecio oldhamianus Maxim. Its effects of cytotoxicity, telomerase activity, apoptosis and related genes expression in two human tumor cell lines, human hepatoma cells
In vitro cytotoxic effects of Senecio stabianus Lacaita (Asteraceae) on human cancer cell lines.
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This study is aimed to evaluate the in vitro cytotoxicity of Senecio stabianus Lacaita (Asteraceae) against renal adenocarcinoma ACHN, hormone-dependent prostate carcinoma LNCaP, amelanotic melanoma C32 and human breast adenocarcinoma MCF-7 cell lines. The n-hexane extract showed an interesting
Development of hepatic tumors in rats following ingestion of Senecio longilobus.
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Primary liver tumours in rats following feeding with alkaloids of Senecio jacobaea.
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Tumor inhibitors. XXII. Senecionine and senecionine N-oxide, the active principles of Senecio triangularis.
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The effect of ragwort (Senecio jacobea) on the liver of the domestic fowl (Gallus domesticus) : a histopathological and enzyme histochemical study.
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1. Twenty-five 1-week-old male chicks were fed for 6 weeks on a standard diet incorporating 7% dried and ground ragwort (Senecio jacobea). The chicks received the standard diet for a further 6 weeks whilst a control group of 25 similar birds received the standard diet throughout. 2. Two birds from
Biological properties of different extracts of two Senecio species.
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This study reports on the antioxidant, anti-diabetic and cytotoxic properties of different extracts of two Senecio species, Senecio vulgaris and Senecio inaequidens. Leaves of the latter are used as food in specific populations of Southern of Africa. Both investigated species of Senecio were found
New antimicrobial and cytotoxic benzofuran glucoside from Senecio glaucus L
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The ethyl acetate fraction of the dried aerial parts of Senecio glaucus L. exhibited significant antimicrobial activity against some of selected bacteria and fungi. Also, it showed potent cytotoxicity against PANC-1 cancer cell lines under glucose deficient medium. The ethyl acetate fraction
Jacaranone glycosides from Senecio scandens.
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Bioassay-guided fractionation of the ethanol extract of Senecio scandens led to the isolation of four new compounds 1-4. These compounds were obtained as tautomeric mixture of alpha/beta epimers, but their structures were confirmed unambiguously by 1D and 2D NMR spectra and LC NMR technology. 1H NMR
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