spermine/悪性腫瘍

BACKGROUND OF THE INVENTION 1 Field of the Invention The present invention relates generally to the detection of enzyme levels that are affected by a specific class of cancer chemotherapeutic agents, and more particularly, to the use of the enzyme spermidine/spermine N.sup.1 -acetyltransferase as a

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention

BACKGROUND OF THE INVENTION FIELD OF THE INVENTION The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention has

BACKGROUND OF THE INVENTION FIELD OF THE INVENTION The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention has

FIELD OF THE INVENTION The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention has been focused on the

BACKGROUND OF THE INVENTION Field of the Invention The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention has

BACKGROUND OF THE INVENTION This invention was made with U.S. Government support under Grant NCDDG-CA37606, awarded by the National Cancer Institute. The U.S. Government has certain rights in this invention. 1. Field of the Invention The present invention relates to anti-neoplastic and

FIELD OF THE INVENTION The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention has been focused on the

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention

BACKGROUND OF THE INVENTION FIELD OF THE INVENTION The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects. In recent years a great deal of attention has

FIELD OF THE INVENTION This invention relates to nucleic acid and amino acid sequences of a novel human spermidine/spermine N1-acetyltransferase and to the use of these sequences in the treatment of cancers. BACKGROUND OF THE INVENTION The polyamines, putrescine, spermidine, and spermine are

FIELD OF THE INVENTION This invention relates to nucleic acid and amino acid sequences of a novel human spermidine/spermine N1-acetyltransferase and to the use of these sequences in the treatment of cancers. BACKGROUND OF THE INVENTION The polyamines, putrescine, spermidine, and spermine are

TECHNICAL FIELD OF THE INVENTION The present invention provides a class of pharmaceutical compositions useful for the treatment of cancer, particularly solid tumors, and having an immuno-modulating mechanism of action as spermine antagonists. The present pharmaceutical compositions are able to

BACKGROUND OF THE INVENTION The present invention relates to new compounds which are useful in the regulation of the interconversion of polyamines. More specifically, the present invention contemplates inhibitors of spermidine/spermine N.sup.1 -acetyltransferase, which plays a key role in regulating

Pursuant to 37 C.F.R. 1.821(c), a sequence listing is submitted herewith as an ASCII compliant text file named "MESCP0082US_ST25.txt", created on Jul. 26, 2016 and having a size of .about.1 kilobytes. The content of the aforementioned file is hereby incorporated by reference in its