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testosterone/悪性腫瘍

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Prophylactic perioperative testosterone supplementation for protection of and recovery of function

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U.S. GOVERNMENT SUPPORT Not applicable. BACKGROUND OF THE INVENTION 1. Area of the Background This invention is generally in the area of urology and more specifically in improved treatment and outcome for radical prostatectomy surgery. 2. Description of the Background Low testosterone level

Pharmaceutical compositions containing testosterone and an aromatase inhibitor

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BACKGROUND Testosterone, delivered by subcutaneous pellet implant has been used in the United States, Europe and Australia in both men and women to treat symptoms of testosterone deficiency. Symptoms of testosterone hormone deficiency include fatigue, lack of energy, depression, memory loss,
BACKGROUND OF THE INVENTION A. Field of the Invention The invention relates to the use of nutrient combinations to prevent or reduce potential adverse effects from administration of androgenic testosterone precursors to humans and other mammals Specifically, the invention relates to

Methods for decreasing steroidogenesis in prostate cancer cells

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FIELD OF THE INVENTION The present invention relates in general to compositions and methods for treatment of cancer. More specifically, the invention provides compositions and methods for treating diseases such as cancer by disrupting the luteinizing hormone (LH)/luteinizing hormone receptor (LHR)

Method of treating prostate cancer with GnRH antagonist

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Prostate cancer is a leading cause of morbidity and mortality for men in the industrialized world. The American Cancer Society estimates that during 2007 about 218,890 new cases of prostate cancer will have been diagnosed in the United States alone. Prostate cancer is the second leading cause of

Method of treating prostate cancer with GnRH antagonist

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Prostate cancer is a leading cause of morbidity and mortality for men in the industrialized world. The American Cancer Society estimates that during 2007 about 218,890 new cases of prostate cancer will have been diagnosed in the United States alone. Prostate cancer is the second leading cause of

Method of treating prostate cancer with GnRH antagonist

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Prostate cancer is a leading cause of morbidity and mortality for men in the industrialized world. The American Cancer Society estimates that during 2007 about 218,890 new cases of prostate cancer will have been diagnosed in the United States alone. Prostate cancer is the second leading cause of

Indole derivatives useful as testosterone 5.alpha.-reductase inhibitors

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This application is a National Stage application of PCT/JP94/00406, filed Mar. 14, 1994, which published as WO94/22821 on Oct. 13, 1994. TECHNICAL FIELD The present invention relates to novel indole derivatives and pharmaceutically acceptable salts thereof. More particularly, it relates to novel

Inhibitors for testosterone 5.alpha.-reductase activity

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FIELD OF THE INVENTION This invention relates to pharmaceutical compositions and methods for the treatment of androgen-related diseases, said compositions having novel inhibitors of testosterone 5.alpha.-reductase activity. The inhibitors have a good combination of inhibitory effect on

Testosterone compounds and use for the protection of neurons

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TECHNICAL FIELD The present invention relates to novel methods for conferring neuroprotection on a subject that relies on administering an effective dose of at least one testosterone inhibitor. BACKGROUND TO THE INVENTION Neurodegenerative diseases have a major impact on society. For example,

Methods and compositions for the identification and assessment of prostate cancer therapies and the diagnosis of prostate cancer

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BACKGROUND OF THE INVENTION Prostate cancer is the most commonly diagnosed cancer in American men and the second most common cause of death from cancer in American men. Androgen withdrawal, by castration or through the use of an anti-androgenic drug, is the preferred treatment method for prostate

Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides

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FIELD OF THE INVENTION This application relates to a method and compositions for chemosensitization and radiosensitization of cancer cells through administration of compositions, such as antisense oligonucleotides, which reduce the amount of TRPM-2 in the cells. The invention is of particular

Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides

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FIELD OF THE INVENTION This application relates to a method and compositions for chemosensitization and radiosensitization of cancer cells through administration of compositions, such as antisense oligonucleotides, which reduce the amount of TRPM-2 in the cells. The invention is of particular

Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides

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FIELD OF THE INVENTION This application relates to a method and compositions for chemosensitization and radiosensitization of cancer cells through administration of compositions, such as antisense oligonucleotides, which reduce the amount of TRPM-2 in the cells. The invention is of particular

Anti-aromatase pharmaceutical composition for controlling testosterone/estrone ratios

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It is known, that throughout life of a mammal or a human being, testosterone/estrone ratios do have a considerable effect on mammal or human life. This testosterone/estrone ratio will exert a powerful and considerable reactions to the emotional well being, as well as in sexual functions, libido,
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