12 結果
FIELD OF THE INVENTION
The present invention relates to a novel crystalline form of topotecan monohydrochloride pentahydrate, corresponding pharmaceutical compositions, methods of preparation and/or use thereof to treat anti-viral and/or cancer-related diseases.
BACKGROUND OF THE INVENTION
A
FIELD OF INVENTION
The present invention relates to the field of medicine. More particularly, the invention relates to compounds, pharmaceutical compositions and uses thereof for the treatment of cancers.
BACKGROUND OF INVENTION
Cancer refers to more than one hundred clinically distinct forms of the
FIELD OF INVENTION
The present invention relates to the field of medicine. More particularly, the invention relates to compounds, pharmaceutical compositions and uses thereof for the treatment of cancers.
BACKGROUND OF INVENTION
Cancer refers to more than one hundred clinically distinct forms of the
BACKGROUND OF THE INVENTION
Coadministration of oncolytic viruses with other chemotherapeutic agents is disclosed in WO 00/62735 (pages 35-36). See Kirn D (Cancer Gene Ther 2002; 9:959-960; Virotherapy for cancer: current status, hurdles and future directions) and Bell J C et al. (Cur Gene Ther
FIELD OF THE INVENTION
The present invention relates to combinations and methods for treatment or prevention of neoplasia disorders in a mammal using two or more components with at least one component being a matrix metalloproteinase inhibitor.
BACKGROUND OF THE INVENTION
A neoplasm, or tumor, is an
FIELD OF THE INVENTION
The invention relates to novel alkyne-, azide- and triazole-containing flavonoid compounds, methods of preparing the same, and use of these compounds for reducing multidrug resistance caused by overexpression of ABC transporters.
This invention relates to a new method of
FIELD OF THE INVENTION
The invention relates to novel alkyne-, azide- and triazole-containing flavonoid compounds, methods of preparing the same, and use of these compounds for reducing multidrug resistance caused by overexpression of ABC transporters.
This invention relates to a new method of
FIELD OF THE INVENTION
The present invention relates to a novel crystalline form of topotecan monohydrochloride pentahydrate, corresponding pharmaceutical compositions, methods of preparation and/or use thereof to treat anti-viral and/or cancer-related diseases.
BACKGROUND OF THE INVENTION
A
FIELD OF THE INVENTION
The present invention relates generally to the fields of cancer therapy and cancer prevention. More particularly, the present invention generally relates to a diagnostic marker for predicting the efficacy of topoisomerase I (topo I) inhibitors in the treatment of cancers, and
FIELD OF THE INVENTION
The present invention relates to the use of radio-labeled antitumor drugs in the diagnosis and treatment of cancers characterized by solid tumors. The invention also relates to radio-labeled antitumor drugs and their preparation.
BACKGROUND
Cancer treatment has made great
FIELD OF THE INVENTION
The present invention relates to the use of radio-labeled antitumor drugs in the diagnosis and treatment of cancers characterized by solid tumors. The invention also relates to radio-labeled antitumor drugs and their preparation.
Cancer treatment has made great progress in
TECHNOLOGY FIELD
The present invention relates to novel camptothecin derivatives and uses thereof.
BACKGROUND OF THE INVENTION
Cancer is the second leading cause of death in the United States and accounts for the deaths of one of every four Americans. According to the American Cancer Society, 7.6