Kept under observation by the medical staff were 110 patients with mild or moderately severe generalized parodontitis in a sanatorium-preventorium setting. Depending on the severity of the process in the parodontium tissues the patients were given a differentiated treatment (mouth-baths with a
Excessive breakdown of extracellular matrix by metalloproteinases (MMPs) occurs in many pathological conditions, and thus inhibition of MMP activity might have therapeutic potential. The methanolic extract and the identified compounds from the bark of Tristaniopsis calobuxus Brongniart & Gris