Adjuvant effect of high-frequency hyperthermia of the abdominal cavity on the course of transplanted leukemia in AKR mice.

The adjuvant effect of high-frequency hyperthermia of the abdominal cavity was studied in 2-month-old mice of highly leukemic AKR strain treated with cyclophosphamide. Weights of organs, parameters of the peripheral blood, and cytological imprints of organs were compared in experimental and control animals. A more pronounced antitumor effect was observed in animals exposed to hyperthermia. These data provide the basis for clinical use of hyperthermia of the abdominal cavity.