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Natural Product Communications 2015-Mar

Biological activity of the methanol and water extracts of the fruits of anthocyanin-rich plants grown in south-west Poland.

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Paulina Strugala
Anna Dudra
Alicja Z Kucharska
Anna Sokól-Lętowska
Dorota Wojnicz
Agnieszka Cisowska
Stefan Walkowski
Zbigniew Sroka
Janina Gabrielska
Andrzej B Hendrich

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요약

In this study we focused on the chemical composition, antioxidant, anti-inflammatory and antibacterial properties of methanol and water extracts of fruits of six species grown in south-west Poland: blackberry, blackcurrant, chokeberry, cherry, gooseberry and raspberry. No general correlation could be drawn between extract chemical properties (i.e. antioxidant and free radical scavenging) and observed biological effects. However, blackcurrant and blackberry extracts (both methanol and water) appeared to be good antioxidants and free radical scavengers, as well as effective inhibitors of E. coli adhesion to the uroepithelial cells. On the other hand, the poorest antioxidants and free radical scavengers, cherry and gooseberry extracts, also poorly affected bacterial growth, swimming ability and adhesion to epithelial cells. Surprisingly, gooseberry extracts, which showed generally weak effects, appearedto be the most effective inhibitor of bacterial biofilm formation. Additionally, most of the studied extracts showed reasonably strong anti-inflammatory properties.

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