adrenoleukodystrophy/알부민

Adrenoleukodystrophy (ALD) is an inherited disorder of fatty acid metabolism marked by accumulation of very long chain saturated fatty acids (VLCFA), especially the 26-carbon acid, hexacosanoic acid (HA), in membranes and tissues. We have studied interactions of 13C-enriched HA with model membranes

We have studied the metabolism of [17,18-3H2]hexacosanoic acid and [15,16-3H2]lignoceric acid in cultured skin fibroblasts from patients with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN). The successful solubilization of the very long chain fatty acids as albumin conjugates was

Abnormalities in the transport of saturated very long chain fatty acids (VLCFA; >C18:0) contribute to their toxic levels in peroxisomal disorders of fatty acid metabolism, such as adrenoleukodystrophy and adrenomyeloneuropathy. We previously showed that VLCFA desorb much slower than normal dietary

Dimentions of the renal corpuscle, proximal and distal convoluted tubules have been studied in the dog kidney, normal and the morphofunctional state of the organ after cutting and ligation of its different lymphatic vessels (4 series of experiments in 158 dogs). The observations have been performed