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alcoholism/비만증

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A controlled family history study of Tourette's syndrome, II: Alcoholism, drug abuse, and obesity.

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The behaviors associated with Gilles de la Tourette's syndrome (TS), including impulsive, compulsive, attentional, learning, conduct, and mood disorders, have often been described as substrates for the development of alcoholism and/or drug abuse. As the authors' experience with TS pedigrees

Is biology destiny after all? : three clinical conundrums: homosexuality, alcoholism, and obesity.

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Recent announcements about the discovery of a biological/genetic basis for homosexuality compel psychodynamically oriented therapists to reassess once again their understanding of mind/body relations. By comparing the claims made in regard to homosexuality, where a biological basis is pronounced

Familial risk for alcohol dependence and developmental changes in BMI: the moderating influence of addiction and obesity genes.

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OBJECTIVE Familial loading for alcohol dependence (AD) and variation in genes reported to be associated with AD or BMI were tested in a longitudinal study. METHODS Growth curve analyses of BMI data collected at approximately yearly intervals and obesity status (BMI > 30) were

The influence of obesity, alcohol abuse, and smoking on utilization of health care services.

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OBJECTIVE There is extensive evidence relating individual behavioral risk factors to adverse health outcomes and associated costs; however, more-comprehensive assessments have been limited. Our objective was to examine the relative effects of obesity, alcohol abuse, and smoking on health care use

Personal and parental alcohol abuse, and victimization in obese binge eaters and nonbingeing obese.

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Current obesity research has begun to emphasize the importance of pretreatment assessment and more individually tailored treatment protocols. Obese binge eaters have been identified as a subgroup of the obese who do not respond well to standard behavioral treatment programs. We were interested in

The emerging link between alcoholism risk and obesity in the United States.

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BACKGROUND The prevalence of obesity has risen sharply in the United States in the past few decades. Etiologic links between obesity and substance use disorders have been hypothesized. OBJECTIVE To determine whether familial risk of alcohol dependence predicts obesity and whether any such

Hyperuricemia-hyperlipemia association in the absence of obesity and alcohol abuse.

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We carried out a study of 43 male asymptomatic subjects with high levels of uric acid but showing no signs of arterial hypertension, obesity or alcohol abuse. Initially, we investigated cholesterol levels, triglycerides in blood serum and the very low density lipoprotein fraction. The results showed
The expression of the galanin gene (GAL) in the paraventricular nucleus (PVN) and in the amygdala of higher vertebrates suggests the requirement for highly conserved, but unidentified, regulatory sequences that are critical to allow the galanin gene to control alcohol and fat intake and modulate

Hepatic, lipid and genetic factors associated with obesity: crosstalk with alcohol dependence?

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Alcohol dependence represents a leading cause of mortality and morbidity. Understanding the variables that contribute to this diagnosis and its severity is critical. An overlap between factors that may predispose people to become obese and those that may increase the risk of alcohol dependence may

Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations.

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Alcohol addiction may increase the risk of obesity due to shared genetic components. The Copine V (CPNE5) gene is involved in Ca(2+) binding and may play an important role in the development of the central nervous system. This study tested the genetic associations of 77 single-nucleotide

Longitudinal associations among depression, obesity and alcohol use disorders in young adulthood.

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OBJECTIVE This study examined concurrent and prospective relations between clinical depression, obesity and alcohol use disorders during young adulthood to better understand common etiology and the progression of co-occurrence. METHODS Participants were 776 young adults (393 males and 383 females)

Dissociated Accumbens and Hippocampal Structural Abnormalities across Obesity and Alcohol Dependence.

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BACKGROUND Processing of food and drug rewards involves specific neurocircuitry, and emerging evidence implicates subcortical abnormalities, particularly the nucleus accumbens and hippocampus. We specifically hypothesized that these 2 established regions in addiction neurocircuitry are associated

Alcoholism and obesity: overlapping neuropeptide pathways?

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Ethanol is a caloric compound, and ethanol drinking and food intake are both appetitive and consummatory behaviors. Furthermore, both ethanol and food have rewarding properties. It is therefore possible that overlapping central pathways are involved with uncontrolled eating and excessive ethanol
OBJECTIVE To evaluate the influence of chronic alcohol abuse on body composition and energy metabolism in patients affected by chronic alcoholism (group A) compared with a group of healthy social drinkers (group B). METHODS A university hospital clinic in Italy. METHODS A total of 32 alcoholics

Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence.

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OBJECTIVE To investigate whether the FTO rs9939609 A allele (a risk factor for obesity) is associated with measures of alcohol consumption. METHODS Population-based cross-sectional study and two case-control studies. METHODS Poland and the Warsaw area. METHODS A total of 6584 subjects from the
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