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amyloid/경색증

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Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis

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IMPORTANCE AND RELEVANCE TO EDCTP2 Despite considerable ongoing efforts in the development of tools to combat tuberculosis (TB), the disease was responsible for approximately 1.6 million deaths, with 10 million people developing the disease worldwide in 2017 (1). An estimated one million children

Impact of Amyloidosis on TAVI Patients

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Type and design of the study: Multicentric, prospective cohort, observational. Number and characteristics of the patients: 321 patients to whom TAVI has been implanted due to severe degenerative AS. Duration of the study - Recruitment period: All consecutive patients undergoing a non-invasive

Biomarkers and Risk Scores for Risk Stratification of Unstable Angina

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Chest pain accounts for up to 1% of visits to GPs in England, about 700000 visits (5%) to emergency departments and up to 25% of emergency admissions to hospitals. Recent epidemiological studies indicate a substantial and increasing rate of admissions with chest pain even as admissions with acute

Is Tau Protein Linked to Mobility Function?

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Impaired mobility is strongly linked to cognitive function and vice versa. Cognitive functions are strongly associated with mobility function, most commonly assessed using gait speed. In the Health ABC Study, Digit Symbol Substitution Test (DSST) and Modified Mini Mental Status (3MS) scores were

Serum, Dietary and Supplemental Vitamin D's Association With Cognitive Decline

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INTRODUCTION Cognitive impairment, a principal cause for functional disability among the elderly, can lead to dementing illness over time mainly in the forms of Alzheimer's Disease (AD) and vascular dementia (VaD). In fact, AD prevalence is expected to rise, reaching 100 million worldwide by 2050,

Cerebral Infarction and White Substance in Angiopathy Cerebral Amyloid

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Effect of Probiotic Supplementation on Endothelial Function II

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Recently, a direct link between intestinal microbiota, dietary phosphatidylcholine, and promotion of cardiovascular disease has been elegantly demonstrated. In this study, broad spectrum antibiotics were employed to disrupt the intestinal microbiota, and metabolomic analysis identified 3 metabolites

Use Lay Language. CAA-ri : a Series of 28 Patients

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We retrospectively reviewed the clinical, radiological and biological data of 28 consecutive patients with a diagnosis of CAA-ri between 2004 and 2016, in 6 different neurological centers from Occitanie in the south of France (Montpellier, Toulouse, Nimes, Narbonne, Bezier, Perpignan). Inclusion

Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease

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Amyloidosis is a multi-organ syndrome, which usually presents as a restrictive cardiomyopathy (RCM). Transthyretin (TTR) amyloidosis is a subtype of amyloidosis, further subdivided into familial type and senile type. Its pathophysiology consists primarily of abnormal precipitation of transthyretin -

The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage?

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Main objective / secondary The objectives are: - To assess frequency of cortical infarcts in the cohort of patients recruited consecutively likely AAFC GHPSJ since 2007 - To assess the link between the presence of myocardial infarction and the clinical characteristics of patients and - To study the

Investigation of Inflammatory Parameters in a Perioperative Closed-meshed Standard Progress in CPB Patients

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Similarly for early detection of SIRS/Sepsis, interleukin 6 (IL-6) assays have been brought up for discussion and have been studied extensively over last years. IL-6 is pro-and anti-inflammatory cytokine with multimodal functions in physiology and patho- physiology: As a major regulator of hepatic

Magnetic Resonance Imaging-based Comparative Research in Different Mild Cognitive Impairment Subtype

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The investigators use both psychological tests and neuroimage to compare the differences between the two groups. All the participants received a battery of neuropsychological tests to assess general mental status and other cognitive domains, including visual-spatial ability, executive function,

GLP-1 and Hyperoxia for Organ Protection in Heart Surgery

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Patients with coronary artery disease (CAD) have associated atherosclerotic renal and cerebral disease making these organs especially vulnerable to ischemia during open heart surgery. At the Heart Center at Rigshospitalet in Copenhagen the investigators perform more than 1000 open heart surgery

BEAM: Brain-Eye Amyloid Memory Study

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1. Retinal correlations with neurodegeneration: 1. Retinal nerve fiber layer (RNFL) pattern will differ in participants in the MCI and early stages of LBD spectrum, AD, and VCI, relative to normal elders. i) RNFL thinning around the optic disc and macular thinning will correlate with hippocampal
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