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amyloid/inflammation

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Method for treating inflammation associated with amyloid deposits and brain inflammation involving activated microglia

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BACKGROUND OF THE INVENTION 1. Field of the Invention The invention relates to inhibiting amyloid deposit formation and dissolving pre-formed amyloid deposits and to methods and pharmaceutical compositions for treating brain inflammation and for treating inflammation associated with amyloid or
BACKGROUND OF THE INVENTION 1. Field of the Invention The invention relates to inhibiting amyloid deposit formation and dissolving pre-formed amyloid deposits and to methods and pharmaceutical compositions for treating brain inflammation and for treating inflammation associated with amyloid or

Use of isolated bacterial amyloids for treatment of inflammatory disorders or diseases of the epithelium

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FIELD OF THE INVENTION The invention relates to the use of isolated bacterial amyloids or the use of recombinant bacteria for the treatment of inflammatory disorders of the epithelium. SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via

Materials and methods related to the inflammatory effects of secreted amyloid precursor proteins

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BACKGROUND OF THE INVENTION Unchecked inflammation in the brain results in neural tissue necrosis which can manifest as seizures, dementia, loss of mental capacities, or death. For example, epilepsy, dementia due to Alzheimer's disease, stroke and traumatic brain injury have all been linked to

HUCBC treatment of amyloid-associated disease

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FIELD OF INVENTION This invention relates to amyloid protein-based diseases. Specifically, the invention relates to mediators of amyloid peptide levels, immune responses, and treatments of Alzheimer's disease. BACKGROUND OF THE INVENTION Amyloid diseases, such as Alzheimer's disease, Huntington's

HUCBC treatment of amyloid associated disease

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FIELD OF INVENTION This invention relates to amyloid protein-based diseases. Specifically, the invention relates to mediators of amyloid peptide levels, immune responses, and treatments of Alzheimer's disease. BACKGROUND OF THE INVENTION Amyloid diseases, such as Alzheimer's disease, Huntington's

Use of pyridinyl-pyrimidinylamino-benzamide derivatives for the treatment of amyloid related disorders

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The invention relates to the use of compounds (hereinafter: "COMPOUND") or a N-Oxide or a pharmaceutically acceptable salt thereof having an activity on protein kinases VEGFR-2, Tie-2, c-Src, c-Met, FGFR-1, Flt-1, HER-2, c-Abl, c-Raf, PDGFR-beta, c-Kit, or on a combination of the above enzymes, for

Amyloid beta peptides as therapy for multiple sclerosis

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BACKGROUND OF THE INVENTION Multiple Sclerosis (MS) is an autoimmune disease of the CNS of unknown etiology that affects .about.400 000 Americans. In MS, myelin reactive T cells enter into the brain and spinal cord and mediate destruction of the myelin sheath surrounding neurons resulting in

Assay and purification of amyloid components, applications, and kits therefor

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The invention relates to a new method of immunological analysis for serum amyloid A protein (SAA) and serum amyloid P-component (SAP), kits therefor and a method of purification of SAA and SAP. BACKGROUND OF THE INVENTION Following most forms of tissue injury, infection or inflammation, the

Inhibiting amyloid-beta peptide/rage interaction at the blood-brain barrier

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BACKGROUND OF THE INVENTION The invention relates to inhibiting specific receptor-ligand interaction between Alzheimer's amyloid-.beta. peptide (A.beta.) and the Receptor for Advanced Glycation Endproducts (RAGE). A number of genetic, cellular, biochemical, and animal studies suggest accumulation of

Diagnostic assays of secreted biological fluids for detection of infection and inflammatory conditions

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FIELD OF THE INVENTION The present invention relates generally to the field of diagnostics. In particular, the invention provides a method for diagnosing infection and other inflammatory conditions by measuring the presence of Serum Amyloid A in a secreted biological fluid. The invention further

Biomarkers for inflammation of the liver

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RELATED APPLICATIONS This application is a national stage application (under 35 U.S.C. .sctn.371) of PCT/DE2007/001427, filed Aug. 10, 2007, which claims benefit of German application 102006037613.7, filed Aug. 10, 2006 and German application 102006048249.2, filed Oct. 12, 2006. DESCRIPTION The

Model for chronic cerebral inflammation by intracerebral injection of double stranded RNA

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FIELD OF THE INVENTION The present invention relates to an animal model for use in the study of human diseases, conditions and disorders, especially neurodegenerative diseases, that are characterized by the damage or dysfunction of the central nervous system. The present invention also relates to

Cromolyn compositions and methods thereof

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FIELD OF THE INVENTION The invention relates generally to cromolyn compositions and methods thereof. Specifically, the invention relates to effectively delivering cromolyn particles to a patient in need thereof for treating various diseases. BACKGROUND OF THE INVENTION Cromolyn (also known as

Methods for delivering cromolyn

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FIELD OF THE INVENTION The invention relates generally to methods of delivering cromolyn to a patient in need thereof, to methods of treating amyloid-associated conditions and inflammatory or allergic lung diseases, and to blister packs and kits comprising cromolyn. BACKGROUND Cromolyn (also known
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