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A total of 6 patients with bulky pelvic bladder cancer underwent combination cis-diamminedichloroplatinum II (cisplatin) hypogastric artery infusion and local bladder hyperthermia as a preoperative adjunct to radical cystectomy. Pathological examination showed extensive tumor necrosis on the luminal
OBJECTIVE
To evaluate the effectiveness of combined local bladder hyperthermia and intravesical chemotherapy for the treatment of patients with high-grade (G3) superficial bladder cancer.
METHODS
Patients with G3 bladder tumors (Stage Ta or T1) were treated with combined intravesical chemotherapy
Hyperthermia represents a unique, safe, and advantageous methodology for improving therapeutic strategies in the management of bladder cancer. This modality has shown promise in contributing to treatment regimens for both superficial and muscle-invasive disease. Especially in conjunction with
A study of the effect of bladder lavage with isotonic fluid at 45 degrees C on proliferative transitional cell carcinoma has shown definite cancericidal changes. These early studies suggest that further investigation of hyperthermia on a larger scale would be worth while.
Lymphangioma in the bladder is extremely rare. An 8-year-old girl presented with a terminal hematuria associated with intermitted fever. Ultrasonography, computed tomogram, and retrograde urethrography showed a mass that was in the wall of the bladder. The tumor was red and found to be bulging into
OBJECTIVE
The role of a combined regimen of local hyperthermia and topical chemotherapy in patients with multifocal and recurrent superficial bladder tumors not curable by transurethral resection was evaluated in a neoadjuvant organ sparing clinical study.
METHODS
A total of 19 patients with
High temperature bladder irrigation was employed in 4 men as an alternative to cystectomy because of their age and frailty. Hyperthermic irrigation of the bladder from 63 degree C for 70 minutes to 82 degree C for 25 minutes caused partial, but not total, necrosis of the bladder. Transitional cell
Modern cancer care is characterized by a focus on organ-sparing multi-modal treatments. In the case of non-muscle-invasive bladder cancer this is particularly true; treatment is focused on reducing the frequency of low-risk recurrences and preventing high-risk progression. Deep regional hyperthermia
Recurrent non muscle invasive bladder cancer (NMIBC) represents a therapeutic challenge, especially in the case of Bacillus Calmette Guerin (BCG)-failures. Chemohyperthermia (CHT) has been tested as adjuvant therapy in selected categories of patients with promising results. The aim of this
A previously healthy 29-year-old man who had verified Rocky Mountain spotted fever had a flaccid neurogenic bladder that resolved as he recovered from his infection. The neurologic complications of this disease are presumed to be related to vasculitis with resulting ischemia or infarction of nervous
Studies were made on hyperthermic treatment of BC-50 bladder cancer cells in ACI/N rats with the following results: (1) Hyperthermia had a marked cytotoxic effect on BC-50 transitional carcinoma cells in vitro. (2) In vivo, heat treatment for 30 min was insufficient, but heat treatment for 60 min or
Nine patients with bulky pelvic bladder cancer underwent combination doxorubicin hydrochloride hypogastric artery infusion and local bladder hyperthermia as a preoperative adjunct to radical cystectomy in a phase I study. Pathologic examination of the cystectomy specimens showed extensive tumor